TORC1 Signaling in Fungi: From Yeasts to Filamentous Fungi

被引：7
|
作者：
Wang, Yuhua [1 ]
Zheng, Xi [1 ]
Li, Guohong [1 ]
Wang, Xin [1 ]
机构：
[1] Yunnan Univ, State Key Lab Conservat & Utilizat Bioresources Yu, Kunming 650091, Peoples R China
来源：
MICROORGANISMS | 2023年 / 11卷 / 01期
基金：
中国国家自然科学基金;
关键词：
TORC1; Rag-GTPase; yeast; filamentous fungi; amino acids; growth; metabolism; TRANSCRIPTION FACTORS; STRESS-RESPONSE; NITROGEN-SOURCE; RAPAMYCIN TOR; FISSION YEAST; CELL-GROWTH; KINASE; TARGET; PATHWAY; COMPLEX;
D O I：
10.3390/microorganisms11010218
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Target of rapamycin complex 1 (TORC1) is an important regulator of various signaling pathways. It can control cell growth and development by integrating multiple signals from amino acids, glucose, phosphate, growth factors, pressure, oxidation, and so on. In recent years, it has been reported that TORC1 is of great significance in regulating cytotoxicity, morphology, protein synthesis and degradation, nutrient absorption, and metabolism. In this review, we mainly discuss the upstream and downstream signaling pathways of TORC1 to reveal its role in fungi.
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页数：15
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