Mercury and neurodevelopmental disorders in children: A systematic review

被引：2
|
作者：
Tapia, Diana Ealo [1 ]
Abad, Juan Torres [1 ]
Madera, Meisser [2 ]
Lazaro, Johana Marquez [1 ,3 ]
机构：
[1] Corp Univ Rafael Nunez, Med Program, GINUMED Grp, Cartagena, Colombia
[2] Univ Cartagena, Sch Dent, Res Dept, Cartagena, Colombia
[3] Corp Univ Rafael Nunez, Med Program, TOXSA Grp, Cartagena, Colombia
来源：
ARCHIVOS ARGENTINOS DE PEDIATRIA | 2023年 / 121卷 / 05期
关键词：
mercury; neurodevelopmental disorders; autism spectrum disorder; attention deficit hyperactivity disorder; METHYLMERCURY EXPOSURE; ASSOCIATIONS; AUTISM; LEVEL; HEALTH; RISK; AGE; LANGUAGE; IMPACT; BLOOD;
D O I：
10.5546/aap.2022-02838.eng
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Mercury is a toxic metal which can cross the placenta and the blood-brain barrier and cause the disruption of various cellular processes. Studies have investigated mercury exposure and neurodevelopmental disorders; therefore, a critical and rigorous analysis of this evidence is required. The objective of this review was to evaluate the available scientific evidence on the effects of mercury exposure during the prenatal and postnatal periods and its relationship with the development of neurobehavioral disorders. A systematic search of the MEDLINE and ScienceDirect databases was conducted; the results were presented in tables and narrative synthesis. Only 31 studies met the eligibility criteria. Overall, the evidence on the effects of mercury exposure and neurodevelopmental disorders in children is limited. Learning disabilities, autism, and attention deficit hyperactivity disorder were some of the reported potential effects.
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页数：13
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