Enabling technologies for process intensification in pharmaceutical research and manufacturing

被引：6

作者：

Xiouras, Christos ^{[1
]}

Kuijpers, Koen ^{[1
]}

Fanfair, Dayne ^{[1
]}

Dorbec, Matthieu ^{[1
]}

Gielen, Bjorn ^{[1
]}

机构：

[1] Janssen Pharmaceut Co Johnson & Johnson, CPDS, Janssen Res & Dev, Turnhoutseweg 30, B-2340 Beerse, Belgium

来源：

CURRENT OPINION IN CHEMICAL ENGINEERING | 2023年 / 41卷

关键词：

MICROWAVE-ASSISTED SYNTHESIS; ORGANIC-SYNTHESIS; TEMPERATURE DISTRIBUTION; CHEMICAL-SYNTHESIS; VORTEX REACTOR; FLOW REACTOR; CO-CRYSTALS; ULTRASOUND; CRYSTALLIZATION; IMPACT;

D O I：

10.1016/j.coche.2023.100920

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A perspective is given on the status and outlook of enabling technologies for process intensification in pharmaceutical research and manufacturing. We focus on three areas: photochemical, ultrasound, and microwave technologies that are, to date, underutilized in the pharmaceutical industry. Herein, we present a review of recent scientific and technological advances in each area with the objective to provide insight and highlight potential applications in the pharmaceutical industry. A perspective is also provided on barriers that must still be overcome to achieve the potential real-world application of these technologies.

引用

页数：10

共 50 条

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