Mass spectrometry-based retina proteomics

被引：3
|
作者：
Prokai, Laszlo [1 ]
Zaman, Khadiza [1 ]
Prokai-Tatrai, Katalin [1 ]
机构：
[1] Univ North Texas, Dept Pharmacol & Neurosci, Hlth Sci Ctr, 3500 Camp Bowie Blvd, Ft Worth, TX 76107 USA
来源：
MASS SPECTROMETRY REVIEWS | 2023年 / 42卷 / 03期
基金：
美国国家卫生研究院;
关键词：
biomarkers; estrogenic retina; photobiology; posttranslational modifications; protein expression; proteomics; retina; retinal diseases; therapeutic targets; 2-DIMENSIONAL GEL-ELECTROPHORESIS; DIFFERENTIALLY EXPRESSED PROTEINS; INTEGRAL MEMBRANE-PROTEINS; OXYGEN-INDUCED RETINOPATHY; OPTIC-NERVE TRANSECTION; SPECTRAL COUNT DATA; PIGMENT EPITHELIUM; POSTTRANSLATIONAL MODIFICATION; MACULAR DEGENERATION; DIABETIC-RETINOPATHY;
D O I：
10.1002/mas.21786
中图分类号：
O433 [光谱学];
学科分类号：
0703 ; 070302 ;
摘要：
A subfield of neuroproteomics, retina proteomics has experienced a transformative growth since its inception due to methodological advances in enabling chemical, biochemical, and molecular biology techniques. This review focuses on mass spectrometry's contributions to facilitate mammalian and avian retina proteomics to catalog and quantify retinal protein expressions, determine their posttranslational modifications, as well as its applications to study the proteome of the retina in the context of biology, health and diseases, and therapy developments.
引用
收藏
页码：1032 / 1062
页数：31
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