Emerging Antifungal Resistance in Fungal Pathogens

被引：0

作者：

Hui, Sui Ting ^{[1
]}

Gifford, Hugh ^{[2
]}

Rhodes, Johanna ^{[1
,3
]}

机构：

[1] Imperial Coll London, MRC Ctr Global Infect Dis Anal, London, England

[2] Univ Exeter, MRC Ctr Med Mycol, Exeter, England

[3] Radboudumc, Dept Med Microbiol, Nijmegen, Netherlands

来源：

CURRENT CLINICAL MICROBIOLOGY REPORTS | 2024年 / 11卷 / 02期

基金：

英国惠康基金;

关键词：

Antifungal drug resistance; Public health; Aspergillus fumigatus; Trichophyton indotineae; Candida auris; One Health; ASPERGILLUS-FUMIGATUS; CANDIDA-AURIS; AZOLE FUNGICIDES; EPIDEMIOLOGY; TERBINAFINE; EMERGENCE; INFECTION; ORIGIN;

D O I：

10.1007/s40588-024-00219-8

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Purpose of ReviewOver recent decades, the number of outbreaks caused by fungi has increased for humans, plants (including important crop species) and animals. Yet this problem is compounded by emerging antifungal drug resistance in pathogenic species. Resistance develops over time when fungi are exposed to drugs either in the patient or in the environment.Recent FindingsNovel resistant variants of fungal pathogens that were previously susceptible are evolving (such as Aspergillus fumigatus) as well as newly emerging fungal species that are displaying antifungal resistance profiles (e.g. Candida auris and Trichophyton indotineae).SummaryThis review highlights the important topic of emerging antifungal resistance in fungal pathogens and how it evolved, as well as how this relates to a growing public health burden.

引用

页码：43 / 50

页数：8

共 50 条

[1] Emerging Antifungal Resistance in Fungal Pathogens
Sui Ting Hui
Hugh Gifford
Johanna Rhodes
[J]. Current Clinical Microbiology Reports, 2024, 11 : 43 - 50
[2] Emerging Threats in Antifungal-Resistant Fungal Pathogens
Sanglard, Dominique
[J]. FRONTIERS IN MEDICINE, 2016, 3
[3] Antifungal susceptibility of emerging dimorphic fungal pathogens in the Ajellomycetaceae
Dukik, K.
Al-Hatmi, A. M. S.
Curfs-Breuker, I.
Faro, D.
Meis, J. F.
deHoog, G. S.
[J]. MYCOSES, 2017, 60 : 27 - 27
[4] Resistance of human fungal pathogens to antifungal drugs
Sanglard, D
[J]. CURRENT OPINION IN MICROBIOLOGY, 2002, 5 (04) : 379 - 385
[5] Beyond resistance: antifungal heteroresistance and antifungal tolerance in fungal pathogens
Yang, Feng
Berman, Judith
[J]. CURRENT OPINION IN MICROBIOLOGY, 2024, 78
[6] In vitro susceptibility of uncommon and emerging fungal pathogens to antifungal drugs
Meletiadis, J.
[J]. MYCOSES, 2009, 52 : 5 - 5
[7] Fun(gi)omics: Advanced and Diverse Technologies to Explore Emerging Fungal Pathogens and Define Mechanisms of Antifungal Resistance
Ball, B.
Langille, M.
Geddes-McAlister, J.
[J]. MBIO, 2020, 11 (05):
[8] EMERGING FUNGAL PATHOGENS
ANAISSIE, EJ
BODEY, GP
RINALDI, MG
[J]. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 1989, 8 (04) : 323 - 330
[9] Emerging fungal pathogens
Samonis, G
Maraki, S
Georgiladakis, A
[J]. MEDICAL MICROBIOLOGY LETTERS, 1996, 5 (06): : 310 - 314
[10] Post-transcriptional control of antifungal resistance in human fungal pathogens
Sharma, Cheshta
Kadosh, David
[J]. CRITICAL REVIEWS IN MICROBIOLOGY, 2023, 49 (04) : 469 - 484

← 1 2 3 4 5 →