Granulomatous myopathy co-existent immune-mediated necrotizing myopathy: A case report

被引：0
|
作者：
Yin, Chunli [1 ]
Yin, Shimin [2 ]
Zheng, Danfeng [3 ]
Huang, Ling [2 ]
Fu, Qiuzhen [2 ]
机构：
[1] Anhui Med Univ, Clin Coll 5, Hefei 230032, Peoples R China
[2] PLA Rocket Force Characterist Med Ctr, Dept Neurol, Beijing 100086, Peoples R China
[3] Peking Univ, Peking Univ Hosp 3, Dept Pathol, Sch Basic Med Sci, Beijing 100191, Peoples R China
来源：
CLINICAL NEUROLOGY AND NEUROSURGERY | 2023年 / 232卷
关键词：
Granulomatous myopathy; Sarcoidosis; Anti-SRP antibody; Immune-mediated necrotizing myopathy; Non-caseating granuloma;
D O I：
10.1016/j.clineuro.2023.107844
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Granulomatous myopathy (GM) is a rare disease characterized by non-caseating inflammation of the skeletal muscle, with sarcoidosis as a common cause. Here, we report a case of GM co-existent immune-mediated necrotizing myopathy (IMNM) in which an anti-signal recognition particle (SRP) antibody was positive and a muscle biopsy showed a non-caseating granulomatous structure, along with myofiber necrosis and inflammatory cell infiltration.
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