Novel Combination Approaches to Locoregional and Systemic Therapy in the Management of Primary and Metastatic Liver Tumors

被引：0

作者：

Dai, Michelle ^{[1
,2
]}

Tiu, Bryan-Clement Y. ^{[3
]}

Chen, Millennie ^{[4
]}

Sing, Caitlyn ^{[3
]}

Sharma, Vinay ^{[3
]}

Hoyos, Juan Pablo ^{[3
]}

Scherr, Riley ^{[3
]}

Lin, Wei Ju ^{[2
]}

Breuer, Joseph A. ^{[3
]}

Dayyani, Farshid ^{[5
]}

Imagawa, David ^{[6
]}

Abi-Jaoudeh, Nadine ^{[7
]}

机构：

[1] Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA

[2] Touro Univ Nevada, Coll Osteopath Med, Henderson, NV 89014 USA

[3] Univ Calif Irvine, Sch Med, Irvine, CA USA

[4] Univ Calif Riverside, Sch Med, Riverside, CA USA

[5] Univ Calif Irvine, Dept Med, Div Hematol & Oncol, Orange, CA USA

[6] Univ Calif Irvine, Dept Surg, Orange, CA 92868 USA

[7] Univ Calif Irvine, Dept Radiol Sci, Orange, CA 92868 USA

来源：

CLINICAL ADVANCES IN HEMATOLOGY & ONCOLOGY | 2023年 / 21卷 / 12期

关键词：

Ablation; hepatocellular carcinoma; immune checkpoint inhibitor; radioembolization; transarterial chemoembolization; tyrosine kinase inhibitor; TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION; ADVANCED HEPATOCELLULAR-CARCINOMA; ENDOTHELIAL GROWTH-FACTOR; PHASE-III; TRANSARTERIAL CHEMOEMBOLIZATION; RADIOFREQUENCY ABLATION; NONALCOHOLIC STEATOHEPATITIS; DOUBLE-BLIND; SORAFENIB; CANCER;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Several pathways and mutations must develop or be in place for the onset of cancer. Therefore, therapies should ideally target as many of these pathways as possible to improve outcomes. Combin-ing several agents has proven to be more effective than the use of monotherapy in the treatment of renal cell carcinoma, hepatocellular carcinoma, and other cancers. Combination therapy can also include locoregional therapies such as ablation and embolization with system-ic agents for synergistic effects. This review article discusses the current literature and clinical trials covering these multifactorial combination therapies in primary and metastatic liver tumors.

引用

页码：633 / 648

页数：16

共 50 条

[1] Contemporary Management of Metastatic Gastrointestinal Stromal Tumors: Systemic and Locoregional Approaches
Ang, Celina
Maki, Robert G.
ONCOLOGY AND THERAPY, 2016, 4 (01) : 1 - 16
[2] Contemporary Management of Metastatic Gastrointestinal Stromal Tumors: Systemic and Locoregional Approaches
Celina Ang
Robert G. Maki
Oncology and Therapy, 2016, 4 (1) : 1 - 16
[3] Role of Locoregional and Systemic Approaches for the Treatment of Patients with Metastatic Neuroendocrine Tumors
Miral Sadaria Grandhi
Kelly J. Lafaro
Timothy M. Pawlik
Journal of Gastrointestinal Surgery, 2015, 19 : 2273 - 2282
[4] Role of Locoregional and Systemic Approaches for the Treatment of Patients with Metastatic Neuroendocrine Tumors
Grandhi, Miral Sadaria
Lafaro, Kelly J.
Pawlik, Timothy M.
JOURNAL OF GASTROINTESTINAL SURGERY, 2015, 19 (12) : 2273 - 2282
[5] Complications and Management of Microwave Coagulation Therapy for Primary and Metastatic Liver Tumors
Shinya Shimada
Masahiko Hirota
Toru Beppu
Teishi Matsuda
Naoko Hayashi
Satoshi Tashima
Eiji Takai
Kenji Yamaguchi
Kotaro Inoue
Michio Ogawa
Surgery Today, 1998, 28 : 1130 - 1137
[6] Complications and management of microwave coagulation therapy for primary and metastatic liver tumors
Shimada, S
Hirota, M
Beppu, T
Matsuda, T
Hayashi, N
Tashima, S
Takai, E
Yamaguchi, K
Inoue, K
Ogawa, M
SURGERY TODAY-THE JAPANESE JOURNAL OF SURGERY, 1998, 28 (11): : 1130 - 1137
[7] Radiation therapy for primary and metastatic tumors of the liver
Tsai, Chiao-Ling
Chung, Hans T.
Chu, William
Cheng, Jason Chia-Hsien
JOURNAL OF RADIATION ONCOLOGY, 2012, 1 (03) : 227 - 237
[8] Surgical therapy of primary and metastatic tumors in the liver
Nagel, M
Konopke, R
Ockert, D
Saeger, HD
MEDIZINISCHE WELT, 2001, 52 (1-2): : 8 - 13
[9] Surgical and nonsurgical management of primary and metastatic liver tumors
Zibari, GB
Riche, A
Zizzi, HC
McMillan, RW
Aultman, DF
Boykin, KN
Gonzalez, E
Nandy, I
Dies, DF
Gholson, CF
Holcombe, RF
McDonald, JC
AMERICAN SURGEON, 1998, 64 (03) : 211 - 220
[10] Systemic and Targeted Therapy for Biliary Tract Tumors and Primary Liver Tumors
Thomas, Melanie Byrne
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA, 2014, 23 (02) : 369 - +

← 1 2 3 4 5 →