Shortwave infrared fluorescence imaging of peripheral organs in awake and freely moving mice

被引：1

作者：

Arus, Bernardo A. ^{[1
,2
,3
,4
,5
,6
]}

Cosco, Emily D.

Yiu, Joycelyn ^{[1
]}

Balba, Ilaria ^{[1
]}

Bischof, Thomas S. ^{[1
,2
,3
,4
,5
,6
]}

Sletten, Ellen M.

Bruns, Oliver T. ^{[1
,2
,3
,4
,5
,6
]}

机构：

[1] Helmholtz Zentrum Munchen, Helmholtz Pioneer Campus, Neuherberg, Germany

[2] German Canc Res Ctr, Heidelberg, Germany

[3] Natl Ctr Tumor Dis NCT UCC, Dresden, Germany

[4] Tech Univ Dresden, Med Fak, Dresden, Germany

[5] Tech Univ Dresden, Univ Hosp Carl Gustav Carus, Dresden, Germany

[6] Helmholtz Zentrum Dresden Rossendorf HZDR, Dresden, Germany

来源：

FRONTIERS IN NEUROSCIENCE | 2023年 / 17卷

关键词：

optical imaging; fluorescence; in vivo imaging; awake imaging; fluorescent dyes; near infrared (NIR)-II; organic fluorophores; polymethine dyes; BIOMEDICAL-RESEARCH; RESTRAINT STRESS; II FLUORESCENCE; BRAIN; ANESTHESIA; WINDOW;

D O I：

10.3389/fnins.2023.1135494

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Extracting biological information from awake and unrestrained mice is imperative to in vivo basic and pre-clinical research. Accordingly, imaging methods which preclude invasiveness, anesthesia, and/or physical restraint enable more physiologically relevant biological data extraction by eliminating these extrinsic confounders. In this article, we discuss the recent development of shortwave infrared (SWIR) fluorescent imaging to visualize peripheral organs in freely-behaving mice, as well as propose potential applications of this imaging modality in the neurosciences.

引用

页数：8

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