Two new quinolinone glycoalkaloids from Chrysanthemum indicum L. and their antimicrobial activity

被引：4
|
作者：
Zhu, Qingsong [1 ]
Liu, Songhu [1 ]
Zhai, Min [1 ]
Qiao, Xinrong [1 ]
Chen, Qiong [1 ]
Zhu, Nailiang [1 ]
机构：
[1] Xinyang Agr & Forestry Univ, Xinyang, Henan, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2023年
关键词：
Chrysanthemum indicum L; compositae; quinolinone glycoalkaloids; antimicrobial activity; ALKALOIDS; CONSTITUENTS; EXTRACTS;
D O I：
10.1080/14786419.2023.2262719
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Phytochemical investigation of Chrysanthemum indicum L. yielded two new quinolinone glycoalkaloids named as Chrysanthemumsides A-B (1-2). The structures of the new compounds were elucidated by analysis of their 1D- and 2D-NMR, HRESIMS and ECD calculations. Compounds 1-4 were evaluated for antimicrobial activity against the Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans, and the data showed that compound 2 had significant antimicrobial effects (MIC 3.9 to 7.8 mu g/mL).
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页数：8
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