CHEMICAL COMPOSITION AND ACETYLCHOLINESTERASE ACTIVITY OF Syzygium pyrifolium (Blume) DC. ESSENTIAL OIL

被引:1
|
作者
Kadir, N. H. A. [1 ]
Salleh, W. M. N. H. W. [1 ,2 ]
Ghani, N. A. [3 ,4 ]
Khamis, S. [2 ,5 ]
Juhari, M. A. A. [2 ,5 ]
机构
[1] Univ Pendidikan Sultan Idris, Dept Chem, Fac Sci & Math, Tanjong Malim 35900, Perak, Malaysia
[2] Univ Kebangsaan Malaysia, Fac Sci & Technol, Frasers Hill Res Ctr, Bangi 43600, Selangor, Malaysia
[3] Univ Teknol MARA, Atta Ur Rahman Inst Nat Prod Discovery AuRIns, Puncak Alam Campus, Bandar Puncak Alam 42300, Selangor, Malaysia
[4] Univ Teknol MARA, Fac Appl Sci, Shah Alam 40450, Selangor, Malaysia
[5] Univ Kebangsaan Malaysia, Fac Sci & Technol, Dept Biol Sci & Biotechnol, Bangi 43600, Selangor, Malaysia
关键词
essential oil; Myrtaceae; Syzygium pyrifolium; GC-MS; geraniol; cholinesterase;
D O I
10.52292/j.laar.2023.1121
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
This study aims to investigate the chemical composition and acetylcholinesterase activity of essential oil from Syzygium pyrifolium leaves. The essential oil was obtained by hydrodistillation in a Clevenger- type apparatus and its chemical composition was analyzed by gas chromatography ( GC-FID) and gas chromatography-mass spectrometry (GCMS). Thirty-two volatile components were identified in S. pyrifolium leaves oil, including geraniol (73.8%), beta- pinene (7.0%), alpha-pinene (5.7%) and (E)-beta-ocimene (4.5%) as the major components. Acetylcholinesterase activity was evaluated using Ellman method and the essential oil showed strong inhibitory activity (I%: 82.5%). Our findings demonstrate that S. pyrifolium essential oil could be useful for an alternative raw material of food and medicinal products for pharmaceutical applications.
引用
收藏
页码:357 / 359
页数:3
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