Impact of atopic dermatitis on occupational contact dermatitis among young people: A retrospective cohort study

被引:2
|
作者
Dietz, Jojo B. [1 ,2 ,8 ]
Menne, Torkil [1 ]
Meyer, Harald W. [3 ]
Viskum, Sven [4 ]
Flyvholm, Mari-Ann [5 ]
Ahrensboll-Friis, Ulrik [1 ]
John, Swen M. [6 ,7 ]
Johansen, Jeanne D. [1 ,2 ]
机构
[1] Copenhagen Univ Hosp Gentofte, Dept Dermato Allergol, Natl Allergy Res Ctr, Hellerup, Denmark
[2] Univ Copenhagen, Copenhagen, Denmark
[3] Univ Copenhagen, Bispebjerg & Frederiksberg Hosp, Dept Occupat & Environm Med, Copenhagen, Denmark
[4] Univ Copenhagen, Unit Social Med, Hosp Frederiksberg, Frederiksberg, Denmark
[5] Natl Res Ctr Working Environm, Copenhagen, Denmark
[6] Univ Osnabruck, Dept Dermatol Environm Hlth & Hlth Theory, Osnabruck, Germany
[7] Univ Osnabruck, Inst Interdisciplinary Dermatol Prevent & Rehabil, Osnabruck, Germany
[8] Gentofte Univ Hosp, Natl Allergy Res Ctr, Gentofte Hospitalsvej 20A,1 Sal, DK-2900 Hellerup, Denmark
关键词
allergic contact dermatitis; atopic dermatitis; irritant contact dermatitis; occupational; QUALITY-OF-LIFE; HAND ECZEMA; FILAGGRIN GENE; SKIN-DISEASE; POPULATION; PREVALENCE; SEVERITY; MUTATIONS; RISK;
D O I
10.1111/cod.14426
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
BackgroundOccupational contact dermatitis (OCD) is a common occupational disease. Atopic dermatitis (AD) is a known risk factor for OCD.ObjectivesTo determine the prevalence of previously diagnosed AD among young workers with recognized OCD and assess its impact on OCD prognosis.MethodsA retrospective cohort study. A questionnaire was sent to 6251 workers with recognized OCD who were under 35 years at notification (response rate: 47%). Of the respondents, 2392 answered a question about previous doctor-diagnosed AD and were included in the study. Eczema severity, occupational consequences and quality of life were examined using statistical analyses comparing workers with and without previously diagnosed AD.ResultsThe prevalence of previously diagnosed AD was 41.8% (95% CI: 39.8-43.8). Women had a higher AD prevalence, and workers with AD reported OCD at a younger age. Workers with AD reported more frequent and severe eczema symptoms and had a higher risk of OCD negatively affecting job and occupation choices. Health-related quality of life was more adversely affected in workers with AD.ConclusionsAD significantly impacts severity and has long-term consequences for young people with OCD. Targeted prevention strategies need to be developed.
引用
收藏
页码:143 / 152
页数:10
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