Migraine Treatment and Healthcare Resource Utilization in Alberta, Canada

被引:0
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作者
Graves, Erin [1 ]
Cowling, Tara [1 ]
McMullen, Suzanne [1 ]
Ekwaru, Paul [1 ]
Pham, Tram [1 ]
Mayer, Michelle [1 ]
Ladouceur, Marie-Pier [2 ]
Hubert, Martine [2 ]
Bougie, Joanna [2 ]
Amoozegar, Farnaz [3 ]
机构
[1] Medlior Hlth Outcomes Res Ltd, Calgary, AB, Canada
[2] Lundbeck Canada Inc, Montreal, PQ, Canada
[3] Univ Calgary, Cumming Sch Med, Dept Clin Neurosci, Calgary, AB, Canada
关键词
Migraine; headache; healthcare utilization; treatment patterns; SOCIETY GUIDELINE; OPIOID USE; HEADACHE; PROPHYLAXIS; ADHERENCE; PATTERNS; IMPACT; COST;
D O I
10.1017/cjn.2023.299
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Background:Migraine poses a significant burden worldwide; however, there is limited evidence as to the burden in Canada. This study examined the treatment patterns, healthcare resource use (HRU), and costs among newly diagnosed or recurrent patients with migraine in Alberta, Canada, from the time of diagnosis or recurrence.Methods:This retrospective observational study utilized administrative health data from Alberta, Canada. Patients were included in the Total Migraine Cohort if they had: (1) >= 1 International Classification of Diseases diagnostic code for migraine; or (2) >= 1 prescription dispense(s) for triptans from April 1, 2012, to March 31, 2018, with no previous diagnosis or dispensation code from April 1, 2010, to April 1, 2012.Results:The mean age of the cohort (n = 199,931) was 40.0 years and 72.3% were women. The most common comorbidity was depression (19.7%). In each medication class examined, less than one-third of the cohort was prescribed triptans and fewer than one-fifth was prescribed a preventive. Among patients with >= 1 dispense, the mean rate of opioid prescriptions was 4.61 per patient-year, compared to 2.28 triptan prescriptions per patient-year. Migraine-related HRU accounted for 3%-10% of all use.Conclusion:Comorbidities and high all-cause HRU were observed among newly diagnosed or recurrent patients with migraine. There is an underutilization of acute and preventive medications in the management of migraine. The high rate of opioid use reinforces the suboptimal management of migraine in Alberta. Migraine management may improve by educating healthcare professionals to optimize treatment strategies. Le traitement de la migraine et l'utilisation des soins de sante en Alberta, au Canada.Contexte :La migraine impose un lourd fardeau dans le monde entier, mais l'on dispose de peu de donnees probantes sur le probleme au Canada. L'etude visait donc a examiner les formes de traitement, l'utilisation des soins de sante (USS) et les couts engendres depuis la pose d'un nouveau diagnostic de migraine ou la survenue de recidives parmi les malades touches en Alberta, au Canada.Methode :Il s'agit d'une etude d'observation retrospective, qui repose sur des donnees administratives sur la sante, provenant de l'Alberta. Les sujets etaient admis dans la cohorte Total Migraine si : 1) >= 1 code de diagnostic de migraine selon la Classification internationale des maladies etait inscrit dans leur dossier; ou 2) >= 1 ordonnance de triptan avait ete executee, du 1er avril 2012 au 31 mars 2018, et ce, sans inscription anterieure de code de diagnostic ou d'execution d'ordonnance, du 1er avril 2010 au 1er avril 2012.Resultats :L'age moyen de la cohorte (n = 199 931) etait de 40,0 ans, et il y avait 72,3 % de femmes. La maladie concomitante la plus frequente etait la depression (19,7 %). Pour chacune des classes de medicaments etudiee, moins de un tiers de la cohorte avait une recu une ordonnance de triptan et moins de un cinquieme de la cohorte avait recu une ordonnance de medicaments de prevention. Parmi les patients ayant >= 1 execution d'ordonnance, le taux moyen d'ordonnance d'opioides etait de 4,61 par patient-annee, comparativement a 2,28 pour les triptans. L'USS liee a la migraine representait de 3 % a 10 % de l'utilisation totale des ressources.Conclusion :La presence de maladies concomitantes et une USS elevee toutes causes confondues ont ete observees parmi les patients chez qui un nouveau diagnostic de migraine avait ete pose et chez ceux qui avaient fait des recidives. Il ressort de l'etude une utilisation insuffisante des medicaments en phase aigue et a titre preventif. Le taux eleve d'utilisation des opioides vient confirmer la prise en charge sous-optimale de la migraine en Alberta. La situation pourrait se corriger par une formation sur l'amelioration des strategies de traitement de la migraine, donnee aux professionnels de la sante.
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