Assessment of the RAD51 test to determine homologous recombination deficiency (HRD) in patients (pts) with newly diagnosed advanced high-grade epithelial ovarian cancer carcinoma (HGOC)

被引:0
|
作者
Duran, C. Garcia [1 ]
Domenech, H. [2 ]
Javierre, G. Villacampa [3 ]
Farinas Madrid, L. [4 ]
Simonetti, S. [5 ]
Illescas, D. G. [1 ]
Serra Elizalde, V. [6 ]
Grau Bejar, J. F. [2 ]
Mazzeo, R. [7 ]
Llop-Guevara, A. [8 ]
Oaknin, A. [1 ]
机构
[1] Vall dHebron Univ Hosp, Med Oncol Dept, Barcelona, Spain
[2] VHIO Vall dHebron Inst Oncol, Expt Therapeut Grp, Barcelona, Spain
[3] Vall dHebron Inst Oncol VHIO, Stat Dept, Barcelona, Spain
[4] Vall dHebron Inst Oncol VHIO, Oncol Dept, Cellex Ctr, Barcelona, Spain
[5] Vall dHebron Inst Oncol VHIO, Mol Oncol Grp, Cellex Ctr, Barcelona, Spain
[6] Vall dHebron Inst Oncol VHIO, Expt Therapeut Grp Dept, Cellex Ctr, Barcelona, Spain
[7] Univ Udine, Med Oncol Dept, Dipartimento Area Med DAME, Udine, Italy
[8] Vall dHebron Inst Oncol VHIO, Expt Therapeut Grp, Cellex Ctr, Barcelona, Spain
关键词
D O I
10.1016/j.annonc.2023.09.1957
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
779P
引用
收藏
页码:S526 / S527
页数:2
相关论文
共 43 条
  • [1] RAD51 as a biomarker for homologous recombination deficiency in high-grade serous ovarian carcinoma: robustness and interobserver variability of the RAD51 test
    Kramer, Claire J. H.
    Llop-Guevara, Alba
    Yaniz-Galende, Elisa
    Pellegrino, Benedetta
    ter Haar, Natalja T.
    Herencia-Ropero, Andrea
    Campanini, Nicoletta
    Musolino, Antonino
    Bosse, Tjalling
    Leary, Alexandra
    Serra, Violeta
    Vreeswijk, Maaike P. G.
    [J]. JOURNAL OF PATHOLOGY CLINICAL RESEARCH, 2023, 9 (06): : 442 - 448
  • [2] Concordance between Three Homologous Recombination Deficiency (HRD) Assays in Patients with High-Grade Epithelial Ovarian Cancer
    Fountzilas, Elena
    Papadopoulou, Kyriaki
    Chatzikonstantinou, Thomas
    Karakatsoulis, Georgios
    Constantoulakis, Pantelis
    Tsantikidi, Aikaterini
    Tsaousis, Georgios
    Karageorgopoulou, Sofia
    Koumarianou, Anna
    Mauri, Davide
    Ntavatzikos, Anastasios
    Saridaki, Zacharenia
    Petrakis, Georgios
    Fostira, Florentia
    Fountzilas, George
    Liontos, Michalis
    [J]. CANCERS, 2023, 15 (23)
  • [3] A RAD51 functional assay as a candidate test for homologous recombination deficiency in ovarian cancer
    Blanc-Durand, Felix
    Yaniz-Galende, Elisa
    Llop-Guevara, Alba
    Genestie, Catherine
    Serra, Violeta
    Herencia-Ropero, Andrea
    Klein, Christophe
    Berton, Dominique
    Lortholary, Alain
    Dohollou, Nadine
    Desauw, Christophe
    Fabbro, Michel
    Malaurie, Emmanuelle
    Bonichon-Lamaichhane, Nathalie
    Dubot, Coraline
    Kurtz, Jean Emmanuel
    de Rauglaudre, Gaetan
    Raban, Nadia
    Chevalier-Place, Annick
    Ferron, Gwenael
    Kaminsky, Marie-Christine
    Kramer, Claire
    Rouleau, Etienne
    Leary, Alexandra
    [J]. GYNECOLOGIC ONCOLOGY, 2023, 171 : 106 - 113
  • [4] Distribution of homologous recombination deficiency (HRD) and BRCA mutations (m) detected by HRD-One test among Brazilian patients (pts) with newly diagnosed advanced epithelial ovarian, fallopian tube, or peritoneal cancer.
    Scaranti, Mariana
    Yamamoto, Guilherme Lopes
    Sousa, Rodrigo Guarischi
    Paniza, Ana Carolina J.
    Milanezi, Fernanda
    Scapulatempo-Neto, Cristovam
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16) : E17600 - E17600
  • [5] Homologous recombination deficiency (HRD) testing on cell-free tumor DNA in ascites of patients with newly diagnosed advanced epithelial ovarian cancer
    Roussel-Simonin, Cyril
    Blanc-Durand, Felix
    Roueau, Etienne
    Le Formal, Audrey
    Chardin, Laure
    Yaniz, Elisa
    Gouy, Sebastien
    Maulard, Amandine
    Cherrier, Stephanie
    Sanson, Claire
    Mauny, Lea
    Coterret, Sophie
    Zaccarini, Francois
    Tang, Roseline
    Leary, Alexandra
    [J]. CANCER RESEARCH, 2023, 83 (07)
  • [6] In-House Testing for Homologous Recombination Deficiency (HRD) in Mexican Patients with High-Grade Serous Ovarian Cancer
    Abreu-Gonzalez, Melania
    Santillan-Martinez, Rosalia
    Garcia-Ortiz, Ramiro
    Alvarez Ordorica, Oliver
    Martinez-Cannon, Bertha A.
    Hernandez Luis, Gisela
    Tellez Bernal, Eduardo
    Cortes Esteban, Patricia
    Blanco Vazquez, Yazmin C.
    Lopez Rosas, Gilberto
    Gomez Garcia, Eva M.
    Sanchez Llamas, Benito
    Rojas Toledo, Emma X.
    Martinez Gutierrez, Selena
    Azotla Vilchis, Coztli O.
    Rodriguez Munoz, Yolanda F.
    Munoz, Alexia
    Montes-Servin, Edgar
    Mendoza-Maldonado, Lucero
    Vaisman, Carolina E.
    Juarez Rodriguez, Rocio
    Flores Palacios, Jose A.
    Lara Torres, Cesar O.
    [J]. JOURNAL OF MOLECULAR DIAGNOSTICS, 2024, 26 (06): : S53 - S54
  • [7] Homologous recombination repair deficiency (HRD) testing in newly diagnosed advanced-stage epithelial ovarian cancer: A Belgian expert opinion
    Vergote, I
    Denys, H.
    Altintas, S.
    Kerger, J.
    Baurain, J-F
    Bours, V
    Henry, S.
    Van de Vijver, K.
    Lambrechts, D.
    Gennigens, C.
    [J]. FACTS VIEWS AND VISION IN OBGYN, 2022, 14 (02): : 111 - 120
  • [8] Characteristics of homologous recombination deficiency (HRD) in paired primary and recurrent high-grade serous ovarian cancer (HGSOC).
    Patel, Jai Narendra
    Sehouli, Jahid
    Timms, Kirsten
    Solimeno, Cara
    Reid, Julia E.
    Lanchbury, Jerry S.
    Braicu, Ioana
    Darb-Esfahani, Silvia
    Ganapathi, Mahrukh
    Ganapathi, Ram N.
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)
  • [9] Role of BRCA1 promotor methylation in homologous recombination deficiency (HRD) in high-grade ovarian cancer
    Fiegl, H.
    Reimer, D.
    Schnaiter, S.
    Leitner, K.
    Wimmer, K.
    Schamschula, E.
    Steger, K.
    Marth, C.
    Zeimet, A. G.
    [J]. ANNALS OF ONCOLOGY, 2023, 34 : S527 - S527
  • [10] Homologous recombination deficiency in newly diagnosed FIGO stage III/IV high-grade epithelial ovarian cancer: a multi-national observational study
    Morgan, Robert D.
    Clamp, Andrew R.
    Barnes, Bethany M.
    Timms, Kirsten
    Schlecht, Helene
    Yarram-Smith, Laura
    Wallis, Yvonne
    Valganon-Petrizan, Mikel
    MacMahon, Suzanne
    White, Rhian
    Morgan, Sian
    McKenna, Sarah
    Hudson, Emma
    Tookman, Laura
    George, Angela
    Manchanda, Ranjit
    Sundar, Sudha S.
    Nicum, Shibani
    Brenton, James D.
    Kristeleit, Rebecca S.
    Banerjee, Susana
    McNeish, Iain A.
    Ledermann, Jonathan A.
    Taylor, Stephen S.
    Evans, D. Gareth R.
    Jayson, Gordon C.
    [J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2023, 33 (08) : 1253 - 1259