One-Carbon Homologation of α,β-Unsaturated Aldehydes: Access to α-Tertiary β,γ-Unsaturated Aldehydes

被引：2
|
作者：
Delbrassinne, Arnaud [1 ]
Mba, Boris Junior Takam [1 ]
Collard, Laurent [1 ]
Robiette, Raphael [1 ]
机构：
[1] Catholic Univ Louvain, Inst Condensed Matter & Nanosci, Pl Louis Pasteur 1 Box L4-01-02, B-1348 Louvain La Neuve, Belgium
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 26卷 / 40期
关键词：
Epoxide; Homologation; Meinwald; Migration; Rearrangement; MEDIATED ASYMMETRIC EPOXIDATIONS; SELECTIVE HYDROFORMYLATION; REARRANGEMENT; EPOXIDES; OXIDATION;
D O I：
10.1002/ejoc.202300765
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient protocol for the synthesis of enolizable alpha-substituted beta,gamma-unsaturated aldehydes is reported. The developed strategy involves two steps, epoxidation and Meinwald rearrangement, to result in a one-carbon homologation of alpha,beta-unsaturated aldehydes enabling the insertion of a CHR unit.
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页数：5
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