Non-coding RNA and their potential role in cardiovascular diseases

被引：8

作者：

Samra, Monika ^{[1
]}

Srivastava, Kamna ^{[1
]}

机构：

[1] Univ Delhi, Dr BR Ambedkar Ctr Biomed Res, Delhi 110007, India

来源：

GENE | 2023年 / 851卷

关键词：

Non -coding RNAs; Coronary artery Disease; Myocardial infarction; Bioinformatic databases; CIRCULAR RNA; CARDIAC-HYPERTROPHY; PERIPHERAL-BLOOD; EXPRESSION; MICRORNA; DATABASE; SIRNA; HEART; DYSFUNCTION; DOWNSTREAM;

D O I：

10.1016/j.gene.2022.147011

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Background: Cardiovascular diseases are the leading cause of mortality worldwide. The timely diagnosis of CVD is still an unmet challenge. Non-coding RNAs which were earlier considered to be "junk DNA" are now considered to play crucial role as potential transcriptional regulators and therapeutic targets for treatment of CVDs.Methodology: A literature search has been performed on PubMed, SCOPUS where keywords such as "non- coding RNAs" and "coronary artery disease" and "miRNAs" and "Myocardial infarction" or "cardiovascular diseases" were used with no date restriction in writing this review article.Conclusion: This review focus on the role of non- coding RNAs in cardiovascular disease along with the database which can enhance the efficiency of experimental analysis of non-coding RNAs.

引用

页数：8

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