Agent-based models in cellular systems

被引:10
|
作者
Pleyer, Jonas [1 ]
Fleck, Christian [1 ]
机构
[1] Univ Freiburg, Freiburg Ctr Data Anal & Modeling FDM, Freiburg, Germany
关键词
agent-based models (ABM); computer simulation; biological cellular systems; pattern formation; developmental biology; PARTIAL-DIFFERENTIAL-EQUATIONS; SIMULATION; GROWTH; CELLS; FRAMEWORK; ENVIRONMENT; MULTISCALE; SOFTWARE; BIOLOGY;
D O I
10.3389/fphy.2022.968409
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
This mini-review discusses agent-based models as modeling techniques for studying pattern formation of multi-cellular systems in biology. We introduce and compare different agent-based model frameworks with respect to spatial representation, microenvironment, intracellular and extracellular reactions, cellular properties, implementation, and practical use. The guiding criteria for the considered selection of agent-based model frameworks are that they are actively maintained, well documented, and provide a model development workflow.
引用
收藏
页数:9
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