MLH1 promotor methylation in colorectal and endometrial carcinomas from patients with Lynch syndrome

被引：0
|
作者：
Helderman, Noah [1 ]
Andini, Katarina [2 ]
van Leerdam, Monique [3 ,4 ]
van Hest, Liselotte P. [5 ]
Ahadova, Aysel [6 ]
Bosse, Tjalling [7 ]
ten Broeke, Sanne [2 ]
Langers, Alexandra [3 ]
Terlouw, Diantha [7 ]
Kloor, Matthias [6 ]
Smit, Vincent [7 ]
van Wezel, Tom [7 ]
Morreau, Hans [7 ]
Nielsen, Maartje [1 ,7 ]
机构：
[1] Leiden Univ Med Ctr LUMC, Clin Genet, Leiden, Netherlands
[2] Univ Med Ctr Groningen, Clin Genet, Groningen, Netherlands
[3] Leiden Univ Med Ctr LUMC, Gastroenterol & Hepatol, Leiden, Netherlands
[4] Netherlands Canc Inst NKI, Gastrointestinal Oncol, Amsterdam, Netherlands
[5] Amsterdam UMC Iocatie AMC, Clin Genet, Amsterdam, Netherlands
[6] Univ Hosp Heidelberg, German Canc Res Ctr DKFZ, Clin Cooperat Unit Appl Tumor Biol, Heidelberg, Germany
[7] Leiden Univ Med Ctr LUMC, Pathol, Leiden, Netherlands
来源：
EUROPEAN JOURNAL OF HUMAN GENETICS | 2024年 / 32卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
P13.034.B
引用
收藏
页码：555 / 555
页数：1
相关论文
共 50 条
  • [1] MLH1 Promotor Hypermethylation in Colorectal and Endometrial Carcinomas from Patients with Lynch Syndrome
    Helderman, Noah C.
    Andini, Katarina D.
    van Leerdam, Monique E.
    van Hest, Liselotte P.
    Hoekman, Daniel R.
    Ahadova, Aysel
    Bajwa-ten Broeke, Sanne W.
    Bosse, Tjalling
    van der Logt, Elise M. J.
    Imhann, Floris
    Kloor, Matthias
    Langers, Alexandra M. J.
    Smit, Vincent T. H. B. M.
    Terlouw, Diantha
    van Wezel, Tom
    Morreau, Hans
    Nielsen, Maartje
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2024, 26 (02): : 106 - 114
  • [2] Contribution of MLH1 constitutional methylation for Lynch syndrome diagnosis in patients with tumor MLH1 downregulation
    Pinto, Diana
    Pinto, Carla
    Guerra, Joana
    Pinheiro, Manuela
    Santos, Rui
    Vedeld, Hege Marie
    Yohannes, Zeremariam
    Peixoto, Ana
    Santos, Catarina
    Pinto, Pedro
    Lopes, Paula
    Lothe, Ragnhild
    Lind, Guro Elisabeth
    Henrique, Rui
    Teixeira, Manuel R.
    CANCER MEDICINE, 2018, 7 (02): : 433 - 444
  • [3] Germline hypermethylation of the MLH1 promotor region as the cause of Lynch syndrome
    Niessen, R. C.
    Hofstra, R. M. W.
    Kooi, K.
    Ou, J.
    Ferreira, A.
    Berends, M. J. W.
    Hollema, H.
    Kleibeuker, J. H.
    Sijmons, R. H.
    EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, 2008, 20 (07) : A42 - A42
  • [4] Selection of patients with germline MLH1 mutated Lynch syndrome by determination of MLH1 methylation and BRAF mutation
    Hanifa Bouzourene
    Pierre Hutter
    Lorena Losi
    Patricia Martin
    Jean Benhattar
    Familial Cancer, 2010, 9 : 167 - 172
  • [5] Analysis of MLH1 Promoter Methylation in Colorectal and Endometrial Carcinomas Using the MethyLight Assay
    Turner, S. A.
    de Abreu, F. B.
    Liu, E. Z.
    Tsongalis, G. J.
    Lefferts, J. A.
    Tafe, L. J.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2015, 17 (06): : 821 - 821
  • [6] Selection of patients with germline MLH1 mutated Lynch syndrome by determination of MLH1 methylation and BRAF mutation
    Bouzourene, Hanifa
    Hutter, Pierre
    Losi, Lorena
    Martin, Patricia
    Benhattar, Jean
    FAMILIAL CANCER, 2010, 9 (02) : 167 - 172
  • [7] Retained Colorectal Carcinoma MLH1 Expression in Lynch Syndrome Patients Carrying a Germline MLH1 Mutation
    Rosty, Christophe
    Clendenning, Mark
    Win, Aung
    Casey, Graham
    Haile, Robert
    Gallinger, Steve
    Le Marchand, Loic
    Newcomb, Polly
    Potter, John
    Lineor, Noralane
    DeRycke, Melissa
    Thibodeau, Stephen
    Hopper, John
    Jenkins, Mark
    Buchanan, Daniel
    LABORATORY INVESTIGATION, 2015, 95 : 188A - 188A
  • [8] Retained Colorectal Carcinoma MLH1 Expression in Lynch Syndrome Patients Carrying a Germline MLH1 Mutation
    Rosty, Christophe
    Clendenning, Mark
    Win, Aung
    Casey, Graham
    Haile, Robert
    Gallinger, Steve
    Le Marchand, Loic
    Newcomb, Polly
    Paller, John
    Lindor, Noralane
    DeRycke, Melissa
    Thibodeau, Stephen
    Hopper, John
    Jenkins, Mark
    Buchanan, Daniel
    MODERN PATHOLOGY, 2015, 28 : 188A - 188A
  • [9] Utility of MLH1 Methylation Analysis in the Clinical Evaluation of Lynch Syndrome in Women with Endometrial Cancer
    Bruegl, A.
    Djordjevic, B.
    Urbauer, D.
    Luthra, R.
    Broaddus, R.
    LABORATORY INVESTIGATION, 2013, 93 : 491A - 491A
  • [10] Utility of MLH1 Methylation Analysis in the Clinical Evaluation of Lynch Syndrome in Women with Endometrial Cancer
    Bruegl, Amanda S.
    Djordjevic, Bojana
    Urbauer, Diana L.
    Westin, Shannon N.
    Soliman, Pamela T.
    Lu, Karen H.
    Luthra, Rajyalakshmi
    Broaddus, Russell R.
    CURRENT PHARMACEUTICAL DESIGN, 2014, 20 (11) : 1655 - 1663
12345