The roles of long noncoding RNA NEAT1 in cardiovascular diseases

被引：2
|
作者：
Jiang, Xiaoying [1 ]
Zhang, Mingjuan [2 ]
机构：
[1] Xi An Jiao Tong Univ, Sch Basic Med Sci, Dept Biochem & Mol Biol, Hlth Sci Ctr, Xian 710061, Shaanxi, Peoples R China
[2] Xi An Jiao Tong Univ, Affiliated Hosp 2, Dept Cardiol, Xian 710004, Peoples R China
来源：
HYPERTENSION RESEARCH | 2024年 / 47卷 / 03期
基金：
美国国家科学基金会;
关键词：
Long noncoding RNAs; NEAT1; Cardiovascular diseases; PROMOTES; INJURY; PROLIFERATION; APOPTOSIS; CELLS;
D O I：
10.1038/s41440-023-01551-0
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
The morbidity of cardiovascular diseases (CVDs) gradually increases worldwide. Long noncoding RNAs (lncRNAs) are a large class of non-(protein)-coding RNAs with lengths beyond 200 nucleotides. Increasing evidence suggests that lncRNA NEAT1 plays important roles in the pathogenesis of CVDs, such as myocardial infarction, heart failure, myocardial ischemia-reperfusion (I/R) injury, atherosclerosis, hypertension, cardiomyopathy, and others. We summarized the current studies of NEAT1 in CVDs, which shed light on the understanding of the molecular mechanisms of CVDs and understanding the therapeutic potential of NEAT1.
引用
收藏
页码：778 / 789
页数：12
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