Comparison of culture-competent virus shedding duration of SARS-CoV-2 Omicron variant in regard to vaccination status: A prospective cohort study

被引:2
|
作者
Kang, Sung-Woon [1 ]
Park, Heedo [2 ,3 ]
Kim, Ji Yeun [1 ]
Bae, Joon-Yong [2 ]
Park, Man-Seong [2 ,3 ]
Kim, Sung-Han [1 ]
机构
[1] Univ Ulsan, Asan Med Ctr, Dept Infect Dis, Coll Med, Seoul, South Korea
[2] Korea Univ, Dept Biomed Sci, BK21 Grad Program, Coll Med, Seoul 02841, South Korea
[3] Korea Univ, Dept Microbiol, Inst Viral Dis, Vaccine Innovat Ctr, Seoul, South Korea
基金
新加坡国家研究基金会;
关键词
SARS-CoV-2; Infection dynamics; Virus shedding;
D O I
10.1016/j.vaccine.2023.03.044
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Previous studies have shown that fully vaccinated patients with SARS-CoV-2 Delta variants has shorter viable viral shedding period compared to unvaccinated or partially vaccinated patients. However, data about effects of vaccination against the viable viral shedding period in patients with SARS-CoV-2 Omicron variants were limited. We compared the viable viral shedding period of SARS-CoV-2 omicron variant regard to vaccination status. Saliva samples were obtained daily from patients with SARS-CoV-2 Omicron variant, and genomic assessments and virus culture was performed to those samples. We found no difference in viable viral shedding period between fully vaccinated and not or partially vacci-nated, nor between 1st boostered vs non-boostered patients with SARS-CoV-2 Omicron variant. (c) 2023 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2769 / 2772
页数:4
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