Synthesis of 2-Boryl Allylboronates by a Bimetallic Platinum/Zinc-Promoted Diborylation of Propargylic Amines

被引：0

作者：

Shi, Xiao-Nan ^{[1
,2
]}

Wang, Jia-Le ^{[1
,2
]}

Wu, Jiang-Bin ^{[1
,2
]}

Zhuo, Chun-Xiang ^{[1
,2
,3
]}

机构：

[1] Xiamen Univ, State Key Lab Phys Chem Solid Surfaces, Key Lab Chem Biol Fujian Prov, Xiamen 361005, Peoples R China

[2] Xiamen Univ, Coll Chem & Chem Engn, Xiamen 361005, Peoples R China

[3] Xiamen Univ, Shenzhen Res Inst, Shenzhen 518057, Peoples R China

来源：

SYNLETT | 2023年 / 34卷 / 13期

基金：

中国国家自然科学基金;

关键词：

2-boryl allylboronates; propargylic amines; platinum catalysis; bimetallic synergistic effect; diborylation; ALDEHYDE-ALKYNE-AMINE; DIBORATION; ALLENES; ALLYL;

D O I：

10.1055/a-2030-6797

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Boryl allylboronates, which contain both a C(sp(2))-B bond and a C(sp(3))-B bond, are attractive synthetic intermediates due to their diverse reactivity profiles toward a wide range of organic transformations. We report a facile approach to (Z)-2-boryl allylboronates through a Pt/Zn-promoted diborylation reaction of readily available propargylic amines. An array of valuable (Z)-2-boryl allylboronates were obtained in up to 73% yield in the presence of 2.5 mol% of Pt(PPh3)(4) and 50 mol% of ZnBr2.

引用

页码：1573 / 1576

页数：4

共 6 条

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