Fingolimod induced fulminant liver failure requiring liver transplantation: A case report

被引：1
|
作者：
Caliskan, Ali Riza [1 ,6 ]
Harputluoglu, Muhsin Murat Muhip [2 ]
Samdanci, Emine [3 ]
Cirik, Salih [4 ]
Yilmaz, Sezai [5 ]
机构：
[1] Adiyaman Training & Res Hosp, Dept Gastroenterol, Adiyaman, Turkiye
[2] Inonu Univ, Sch Med, Dept Gastroenterol, Malatya, Turkiye
[3] Inonu Univ, Sch Med, Dept Pathol, Malatya, Turkiye
[4] Malatya Training & Res Hosp, Dept Internal Med, Malatya, Turkiye
[5] Inonu Univ, Sch Med, Liver Transplantat Inst, Dept Gen Surg, Malatya, Turkiye
[6] Adiyaman Egitim & Arastirma Hastanesi, Gastroenterol Klin, Adiyaman, Turkiye
来源：
HEPATOLOGY FORUM | 2023年 / 4卷 / 02期
关键词：
Acute liver failure; drug-induced liver injury; fingolimod; liver; transplantation; multiple sclerosis; MULTIPLE-SCLEROSIS; ORAL FINGOLIMOD; SAFETY; EFFICACY;
D O I：
10.14744/hf.2022.2022.0033
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Fingolimod has been used for about ten years to treat multiple recurrent sclerosis. It has been reported that Fingolimod causes an elevation in liver enzymes. In this case report, the clinical and laboratory parameters improved after discontinuation of the drug. However, there is no publication in the literature regarding acute liver failure and liver transplantation following Fingolimod treatment. In this article, we presented a 33 - year - old female patient who developed acute liver failure and underwent liver transplantation after Fingolimod treatment for recurrent multiple sclerosis.
引用
收藏
页码：74 / 77
页数：4
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