Immune dysregulation in Down syndrome

被引：3
|
作者：
Bordon, Yvonne
机构：
[1] Nature Reviews Immunology,
来源：
NATURE REVIEWS IMMUNOLOGY | 2023年 / 23卷 / 04期
关键词：
D O I：
10.1038/s41577-023-00855-z
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The immune system in individuals with Down syndrome is characterized by steady state increases in cytokine expression, T cell activation, atypical B cell responses and the presence of numerous autoantibodies.
引用
收藏
页码：201 / 201
页数：1
相关论文
共 50 条
  • [1] Immune dysregulation in Down syndrome
    Yvonne Bordon
    Nature Reviews Immunology, 2023, 23 : 201 - 201
  • [2] Immune Dysregulation in Children With Down Syndrome
    Huggard, Dean
    Doherty, Derek G.
    Molloy, Eleanor J.
    FRONTIERS IN PEDIATRICS, 2020, 8
  • [3] Autoimmunity in Down Syndrome Linked to Immune System Dysregulation
    Harris, Emily
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2023, 329 (12): : 968 - 968
  • [4] Down Syndrome in Children: A Primary Immunodeficiency with Immune Dysregulation
    Szczawinska-Poplonyk, Aleksandra
    Poplonyk, Natalia
    Awdi, Karina
    CHILDREN-BASEL, 2024, 11 (10):
  • [5] Precocious clonal hematopoiesis in Down syndrome is accompanied by immune dysregulation
    Liggett, L. Alexander
    Galbraith, Matthew D.
    Smith, Keith P.
    Sullivan, Kelly D.
    Granrath, Ross E.
    Enriquez-Estrada, Belinda
    Kinning, Kohl T.
    Shaw, Jessica R.
    Rachubinski, Angela L.
    Espinosa, Joaquin M.
    DeGregori, James
    BLOOD ADVANCES, 2021, 5 (07) : 1791 - 1796
  • [6] Practical Considerations regarding the Immune Dysregulation and Immunodeficiency in Down Syndrome
    Baloh, Carolyn
    Gans, Melissa
    Camacho, Juanita Valdes
    Chaimowitz, Natalia
    Ale, Hanadys
    Lawler, Christin
    Lesmana, Harry
    Lopes, Joao Pedro
    Schmitt, Erica
    Squire, Jacqueline
    Tang, Monica
    Shin, Jenny
    Espinosa, Jaoquin
    CLINICAL IMMUNOLOGY, 2024, 262
  • [7] Interferon-Driven Immune Dysregulation in Down Syndrome: A Review of the Evidence
    Chung, Howard
    Green, Peter H. R.
    Wang, Timothy C.
    Kong, Xiao-Fei
    JOURNAL OF INFLAMMATION RESEARCH, 2021, 14 : 5187 - 5200
  • [8] Dysregulation of the Immune System in a Natural History Study of 1299 Individuals with Down Syndrome
    Gansa, William
    Da Rosa, Joel M. Correa
    Menon, Kartikeya
    Sazeides, Christos
    Stewart, O'Jay
    Bogunovic, Dusan
    JOURNAL OF CLINICAL IMMUNOLOGY, 2024, 44 (06)
  • [9] Immune dysregulation in myelodysplastic syndrome
    Sugimori, Chiharu
    List, Alan F.
    Epling-Burnette, Pearlie K.
    HEMATOLOGY REPORTS, 2010, 2 (01) : 1 - 9
  • [10] DYSREGULATION OF THE INFLAMMASOME IN CHILDREN WITH DOWN SYNDROME
    Worrall, Amy P.
    Gallagher, Eleanor
    Huggard, Dean
    Kelly, Lynne
    Molloy, Eleanor
    ARCHIVES OF DISEASE IN CHILDHOOD, 2019, 104 : A108 - A108
12345