Nursing Intervention in Oral Mucositis After Methotrexate Chemotherapy in Children with Hematological Tumors

被引：0
|
作者：
Yu, Benying [1 ]
Du, Lin [1 ]
Chen, Wenyan [1 ]
Xu, Banghong [2 ]
机构：
[1] Nanjing Med Univ, Hematol & Oncol Dept, Childrens Hosp, Nanjing 210008, Peoples R China
[2] Nanjing Med Univ, Childrens Hosp, Internal Med Dept, Nanjing 210008, Peoples R China
来源：
JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING | 2023年 / 13卷 / 05期
关键词：
Hematological Tumors; Methotrexate; Chemotherapy; OralMucositis; STEM-CELL TRANSPLANTATION; CARE;
D O I：
10.1166/jbt.2023.3306
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
Objective: To explore the nursing intervention and its clinical effect on oral mucositis after methotrexate (MTX) chemotherapy in children with hematological tumors. Methods: Two-hundred children with hematological tumors admitted to Nanjing Children's Hospital between January 2021 and August 2022 and treated with MTX chemotherapy after admission randomly dividing as control and experimental groups (n = 100 every group). Children given conventional clinical nursing and comprehensive oral care. Oral ulcer, quality of life, and satisfaction of children's parents after intervention were compared between 2 groups. Results: SF-36 score after nursing intervention significantly increasing in experimental group compared with that of control group, with a statistically significant difference (p < 0.05). Satisfaction of children's parents significantly improving in experimental group compared with that of control group (p < 0.05). Conclusion: Comprehensive oral nursing intervention is effective in preventing and treating oral mucositis, improving oral cleanliness and comfort, and developing good oral hygiene habits, which is conducive to clinical rehabilitation in children undergoing MTX chemotherapy for hematological tumors.
引用
收藏
页码：738 / 741
页数：4
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