A Novel Attention-Based Model for Semantic Segmentation of Prostate Glands Using Histopathological Images

被引:1
|
作者
Inamdar, Mahesh Anil [1 ]
Raghavendra, U. [2 ]
Gudigar, Anjan [2 ]
Bhandary, Sarvesh [1 ]
Salvi, Massimo [3 ]
Deo, Ravinesh C. [4 ]
Barua, Prabal Datta [5 ,6 ,7 ]
Ciaccio, Edward J. [8 ]
Molinari, Filippo [3 ]
Acharya, U. Rajendra [4 ,9 ]
机构
[1] Manipal Acad Higher Educ, Manipal Inst Technol, Dept Mechatron, Manipal 576104, India
[2] Manipal Acad Higher Educ, Manipal Inst Technol, Dept Instrumentat & Control Engn, Manipal 576104, India
[3] Politecn Torino, Dept Elect & Telecommun, PolitoBIOMed Lab, Biolab, I-10129 Turin, Italy
[4] Univ Southern Queensland, Sch Math Phys & Comp, Springfield, Qld 4300, Australia
[5] Cogninet Australia, Cogninet Brain Team, Sydney, NSW 2010, Australia
[6] Univ Southern Queensland, Sch Business Informat Syst, Fac Business Educ Law & Arts, Toowoomba, Qld 4350, Australia
[7] Univ Technol Sydney, Fac Engn & Informat Technol, Sydney, NSW 2007, Australia
[8] Columbia Univ, Dept Med, New York, NY 10032 USA
[9] Kumamoto Univ, Int Res Org Adv Sci & Technol IROAST, Kumamoto 8600862, Japan
关键词
Prostate cancer; image processing; histopathology images; digital image analysis; computational pathology; artificial intelligence; GLEASON PATTERN 4; INTEROBSERVER-REPRODUCIBILITY; NUCLEI SEGMENTATION; ADENOCARCINOMA; HEMATOXYLIN; CANCER;
D O I
10.1109/ACCESS.2023.3321273
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
One of the foremost causes of death in males worldwide is prostate cancer. The identification, detection and diagnosis of the same is very crucial in saving lives. In this paper, we present an efficient gland segmentation model using digital histopathology and deep learning. These methods have the potential to revolutionize medicine by identifying hidden patterns within the image. The recent improvements in data acquisition, processing and analysis of Deep Learning Models has made Artificial Intelligence driven healthcare a very lucrative area, in terms of data inference and delivering meaningful insights. This study presents an automated method for segmenting histopathological images of human prostate glands. The main focus is developing new methods for segmenting histopathological images of prostate gland using a multi-channel algorithm with an attention mechanism to detect important areas. We compare our results with a host of contemporary techniques and show that our method performs better at the segmentation task for histopathological imagery. Our method is able to delineate gland and background parts with an average Dice-coefficient of 0.9168. In this attention-based model we propose for semantic segmentation of prostate glands the potential to provide accurate segmentation versus tumor features, which has significant implications for medical screening applications.
引用
收藏
页码:108982 / 108994
页数:13
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