Loss of the ROR2 Tyrosine Kinase Receptor is Associated With Dysfunctional Angiogenesis in Pulmonary Hypertension via Inappropriate Focal Adhesion Activation and Disruption of the Endothelial Barrier

被引：0
|
作者：
Mitra, Ankita
Chakraborty, Ananya
Zhong, Brian
Agarwal, Stuti
Heo, Lyong
Nair, Ramesh
Dunn, Alexander R.
Dejesus, Vinicio A.
机构：
来源：
CIRCULATION | 2023年 / 148卷
关键词：
Pulmonary hypertension; Pulmonary vascular biology; Angiogenesis; Pulmonary heart disease; Vascular disease;
D O I：
10.1161/circ.148.suppl_1.14438
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A14438
引用
收藏
页数：2
相关论文
共 6 条
  • [1] Loss of ROR2 Tyrosine Kinase Receptor Is Associated With Dysfunctional Angiogenesis in PAH Via Inappropriate Focal Adhesion Activation and Disruption of the Endothelial Barrier
    Mitra, A.
    Chakraborty, A.
    Zhong, B.
    Nair, R. V.
    Heo, L.
    Agarwal, S.
    Pacheco, A.
    Auer, N.
    Dunn, A.
    Perez, V. De Jesus
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2024, 209
  • [2] ROR2 Deficiency is Associated With Endothelial Dysfunction and Reduced Angiogenesis in Pulmonary Arterial Hypertension
    Chakraborty, Ananya
    Nathan, Abinaya
    Agarwal, Stuti
    Orcholski, Mark
    Yuan, Ke
    Bonnet, Sandra
    Bonnet, Sebastien
    Perez, Vinicio A. Dejesus
    CIRCULATION, 2021, 144
  • [3] LOSS OF ROR2 IS ASSOCIATED WITH ENDOTHELIAL DYSFUNCTION IN PAH VIA INAPPROPRIATE INTEGRIN B1 ACTIVATION
    Mitra, Ankita
    Chakraborty, Ananya
    Zhong, Brian
    Nair, Ramesh
    Heo, Lyong
    Agarwal, Stuti
    Dunn, Alexander
    Chelladurai, Prakash
    Dejesus, Vinicio
    CIRCULATION, 2024, 150
  • [4] Loss of Wnt/Ror2 Signaling is Associated With Reduced Pericyte Recruitment and Impaired Pulmonary Angiogenesis in Idiopathic Pulmonary Arterial Hypertension
    Yuan, Ke
    Orcholski, Mark
    Panaroni, Cristina
    Wu, Joy
    Perez, Vinicio de Jesus
    CIRCULATION, 2013, 128 (22)
  • [5] Loss Of Wnt/ror2 Signaling Is Associated With Reduced Pericyte Recruitment And Impaired Pulmonary Angiogenesis In Idiopathic Pulmonary Arterial Hypertension
    Yuan, K.
    Panaroni, C.
    Liliental, J.
    Wu, J.
    Perez, V. De Jesus
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2014, 189
  • [6] Kaposi's sarcoma-associated herpesvirus-encoded G protein-coupled receptor activation of c-jun amino-terminal kinase/stress-activated protein kinase and lyn kinase is mediated by related adhesion focal tyrosine kinase/proline-rich tyrosine kinase 2
    Munshi, N
    Ganju, RK
    Avraham, S
    Mesri, EA
    Groopman, JE
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (45) : 31863 - 31867
1