Multifunctional role of chitosan in farm animals: a comprehensive review

The deacetylation of chitin results in chitosan, a fibrous-like material. It may be produced in large quantities since the raw material (chitin) is plentiful in nature as a component of crustacean (shrimps and crabs) and insect hard outer skeletons, as well as the cell walls of some fungi. Chitosan is a nontoxic, biodegradable, and biocompatible polygluchitosanamine that contains two essential reactive functional groups, including amino and hydroxyl groups. This unique chemical structure confers chitosan with many biological functions and activities such as antimicrobial, anti-inflammatory, antioxidative, antitumor, immunostimulatory and hypocholesterolemic, when used as a feed additive for farm animals. Studies have indicated the beneficial effects of chitosan on animal health and performance, aside from its safer use as an antibiotic alternative. This review aimed to highlight the effects of chitosan on animal health and performance when used as a promising feed additive.