Stearoyl-CoA desaturase Deficiency Improves Insulin Signaling and Represses De Novo Lipogenesis by Altering Levels and The Fatty Acid Composition of Hepatic Phosphatidylglycerols During High Carbohydrate Feeding

被引：0
|
作者：
Kalyesubula, Mugagga [1 ]
Lefers, Luke [1 ]
Huff, Hailey [1 ]
Cootway, Dylan [1 ]
Miller, Jacqueline [1 ]
Geoghegan, Gisela [1 ]
Dutta, Mainak [1 ]
Simcox, Judith [1 ]
Ntambi, James [1 ]
机构：
[1] Univ Wisconsin, Madison, WI 53706 USA
来源：
JOURNAL OF BIOLOGICAL CHEMISTRY | 2023年 / 299卷 / 03期
关键词：
D O I：
10.1016/j.jbc.2023.103895
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
1989
引用
收藏
页码：S476 / S476
页数：1
相关论文
共 8 条
  • [1] Parallel activation of de novo lipogenesis and stearoyl-CoA desaturase activity after 3 d of high-carbohydrate feeding
    Chong, Mary F-F
    Hodson, Leanne
    Bickerton, Alex S.
    Roberts, Rachel
    Neville, Matt
    Karpe, Fredrik
    Frayn, Keith N.
    Fielding, Barbara A.
    AMERICAN JOURNAL OF CLINICAL NUTRITION, 2008, 87 (04): : 817 - 823
  • [2] Stearoyl-CoA desaturase inhibition is toxic to acute myeloid leukemia displaying high levels of the de novo fatty acid biosynthesis and desaturation
    Dembitz, Vilma
    Lawson, Hannah
    Burt, Richard
    Natani, Sirisha
    Philippe, Celine
    James, Sophie C.
    Atkinson, Samantha
    Durko, Jozef
    Wang, Lydia M.
    Campos, Joana
    Magee, Aoife M. S.
    Woodley, Keith
    Austin, Michael J.
    Rio-Machin, Ana
    Casado, Pedro
    Bewicke-Copley, Findlay
    Rodriguez Blanco, Giovanny
    Pereira-Martins, Diego
    Oudejans, Lieve
    Boet, Emeline
    von Kriegsheim, Alex
    Schwaller, Juerg
    Finch, Andrew J.
    Patel, Bela
    Sarry, Jean-Emmanuel
    Tamburini, Jerome
    Schuringa, Jan Jacob
    Hazlehurst, Lori
    Copland, John A., III
    Yuneva, Mariia
    Peck, Barrie
    Cutillas, Pedro
    Fitzgibbon, Jude
    Rouault-Pierre, Kevin
    Kranc, Kamil
    Gallipoli, Paolo
    LEUKEMIA, 2024, 38 (11) : 2332 - 2343
  • [3] Hepatic Stearoyl-CoA desaturase 1 Deficiency Promotes Liver Inflammation Under High Carbohydrate Low Fat Diet Feeding
    Liu, Xueqing
    Flowers, Matthew
    Miyazaki, Makoto
    Sampath, Harini
    Chu, Kiki
    Ntambi, James
    FASEB JOURNAL, 2008, 22
  • [4] Stearoyl-CoA desaturase-1 deficiency increases hepatic and plasma levels of Saturated Long-Chain Acylcarnitines under a high carbohydrate feeding
    Kalyesubula, Mugagga
    Von Bank, Helaina
    Lefers, Luke
    Huff, Hailey
    Cootway, Dylan
    Miller, Jacqueline
    Simcox, Judith
    Ntambi, James
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2024, 300 (03) : S396 - S396
  • [5] Hepatic Oleate Deficiency Represses De Novo Lipogenesis and Enhances Systemic Glucose Utilization Through FGF21 During High Carbohydrate Feeding
    Ntambi, James Mukasa
    Aljohani, Ahmed
    Bonneville, Abram
    Bond, Laura
    FASEB JOURNAL, 2019, 33
  • [6] Hepatic Stearoyl-CoA desaturase-1 deficiency-mediated activation of mTORC1-PGC-1α axis regulates ER stress during high-carbohydrate feeding
    Aljohani, Ahmed
    Khan, Mohammad Imran
    Syed, Deeba N.
    Abram, Bonneville
    Lewis, Sarah
    Neill, Lucas O'
    Mukhtar, Hasan
    Ntambi, James M.
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [7] Hepatic Stearoyl-CoA desaturase-1 deficiency-mediated activation of mTORC1- PGC-1α axis regulates ER stress during high-carbohydrate feeding
    Ahmed Aljohani
    Mohammad Imran Khan
    Deeba N. Syed
    Bonneville Abram
    Sarah Lewis
    Lucas O’ Neill
    Hasan Mukhtar
    James M. Ntambi
    Scientific Reports, 9
  • [8] Dietary betulinic acid alleviates high carbohydrate diet-induced hepatic de novo lipogenesis through AMPK signaling and improves liver health in channel catfish ( Ictalurus punctatus )
    Liu, Yulong
    Lu, Qisheng
    Han, Guoli
    Zheng, Yutong
    Cao, Jingyue
    Xi, Longwei
    Liu, Haokun
    Jin, Junyan
    Zhang, Zhimin
    Yang, Yunxia
    Zhu, Xiaoming
    Han, Dong
    Xie, Shouqi
    AQUACULTURE REPORTS, 2024, 36
1