Reliable prediction of the motion of FOWT (floating offshore wind turbine) and associated mooring line tension is important in both design and operation/monitoring processes. In the present study, a 5MW OC4 semisubmersible wind turbine is numerically modeled, simulated, and analyzed by the open-source numerical tool, OpenFAST and in-house numerical tool, Charm3D-FAST. Another commercial-level program FASTv8-OrcaFlex is also introduced for comparison for selected cases. The three simulation programs solve the same turbine-floater-mooring coupled dynamics in time domain while there exist minor differences in the details of the program. Both the motions and mooring-line tensions are calculated and compared with the DeepCWind 1/50 scale model-testing results. The system identification between the numerical and physical models is checked through the static-offset test and free-decay test. Then the system motions and mooring tensions are systematically compared among the simulated results and measured values. Reasonably good agreements between the simulation and measurement are demonstrated for (i) white-noise random waves, (ii) typical random waves, and (iii) typical random waves with steady wind. Based on the comparison between numerical results and experimental data, the relative importance and role of the differences in the numerical methodologies of those three programs can be observed and interpreted. These comparative-study results may provide a certain confidence level and some insight of potential variability in motion and tension predictions for future FOWT designs and applications.