No difference in follow-up estimated glomerular filtration rate between hypertensive and matched nonhypertensive kidney donors

被引:0
|
作者
Yang, Eun Hye [1 ]
Shin, Sung [2 ]
Kim, Young Hoon [2 ]
Jeong, In Gab [3 ]
Hong, Bumsik [3 ]
Baek, Chung Hee [1 ]
Kim, Hyosang [1 ]
Kim, Soon Bae [1 ]
机构
[1] Univ Ulsan, Coll Med, Asan Med Ctr, Div Nephrol,Dept Internal Med, Seoul, South Korea
[2] Univ Ulsan, Asan Med Ctr, Dept Surg, Div Kidney & Pancreas Transplantat,Coll Med, Seoul, South Korea
[3] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Urol, Seoul, South Korea
来源
NEFROLOGIA | 2024年 / 44卷 / 01期
关键词
Hypertension; Kidney donor; eGFR; STAGE RENAL-DISEASE; BLOOD-PRESSURE; RISK; DONATION; GFR; TRANSPLANTATION; ASSOCIATION; MDRD;
D O I
10.1016/j.nefro.2021.10.004
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Background: According to current guidelines, kidney donor candidates with controlled hypertension using 1 or 2 antihypertensive drugs may be considered as donor. However, this recommendation is based on the study that antihypertensive drug was initiated in mainly "after donor registration" and this may be white -coat hypertension because of donationrelated anxiety. We compared the follow-up eGFR between kidney donors with preexisting hypertension and matched nonhypertensive donors. Methods: This single -center retrospective study classified 97 living hypertensive donors previously receiving antihypertensive drugs into two groups: 1 drug group (61 donors) and 2 drugs group (36 donors). We compared the follow-up eGFR between each donor previously receiving antihypertensive drugs and three matched nonhypertensive donors in terms of age, sex, and follow-up duration. Results: At a mean (range) of 51 months (12-214) in the 1 drug group, and 54 months (12-175) in the 2 drugs group after donation, there was no significant difference in follow-up eGFR between hypertensive donors previously receiving antihypertensive drugs and matched controls in each group and in total donors. There was no difference in the incidence of the patients with follow-up eGFR < 45 mL/min/m(2) in each group and their matched controls. Multiple linear regression analysis showed that baseline eGFR was the only independent predictor for the final follow-up eGFR in the total donors. Conclusion: Our results support the current guidelines that donor candidates with controlled hypertension using 1 or 2 antihypertensive drugs may be considered as donors, and may increase the strength of this recommendation. (c) 2021 Published by Elsevier Espana, S.L.U. on behalf of Sociedad Espanola de Nefrologia. This is an open access article under the CC BY -NC -ND license (http://creativecommons. org/licenses/by-nc-nd/4.0/).
引用
收藏
页码:32 / 39
页数:8
相关论文
共 50 条
  • [1] Estimated glomerular filtration rate for longitudinal follow-up of living kidney donors
    van Londen, Marco
    Wijninga, Anthony B.
    de Vries, Jannieta
    Sanders, Jan-Stephan F.
    de Jong, Margriet F. C.
    Pol, Robert. A.
    Berger, Stefan P.
    Navis, Gerjan
    de Borst, Martin H.
    [J]. NEPHROLOGY DIALYSIS TRANSPLANTATION, 2018, 33 (06) : 1054 - 1064
  • [2] THE EFFECT OF ANTIHYPERTENSIVE DRUGS ON ESTIMATED GLOMERULAR FILTRATION RATE OF HYPERTENSIVE PATIENTS DURING FOLLOW-UP
    Ptinopoulou, Anastasia
    Pikilidou, Maria
    Tziolas, Ioannis
    Haidich, Anna-Bettina
    Zempekakis, Pantelis
    Lasaridis, Anastasios
    [J]. NEPHROLOGY DIALYSIS TRANSPLANTATION, 2015, 30
  • [3] 20-year longitudinal follow-up of measured and estimated glomerular filtration rate in kidney transplant patients
    Pottel, Hans
    Delay, Agnes
    Maillard, Nicolas
    Mariat, Christophe
    Delanaye, Pierre
    [J]. CLINICAL KIDNEY JOURNAL, 2021, 14 (03) : 909 - 916
  • [4] The association between estimated glomerular filtration rate and cadmium exposure: An 8-year follow-up study
    Chen, Xiao
    Chen, Xin
    Wang, Xinru
    Wang, Miaomiao
    Liang, Yihuai
    Zhu, Guoying
    Jin, Taiyi
    [J]. INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2021, 235
  • [5] Predictors of glomerular filtration rate decline in a hypertensive population. A follow-up study
    Ptinopoulou, A.
    Tziolas, I.
    Pikilidou, M.
    Zebekakis, P.
    Hadjistavri, L.
    Sarafidis, P.
    Papoulidou, F.
    Mouhtaropoulou, E.
    Lasaridis, A.
    [J]. JOURNAL OF HYPERTENSION, 2008, 26 : S431 - S432
  • [6] Improving Evaluation and Follow-Up of Living Kidney Donors: Role of Radioisotopic Glomerular Filtration Rate and Renal Functional Reserve
    Cantaluppi, V.
    Guglielmetti, G.
    Morosini, U. M.
    Nappo, A.
    Merlotti, G.
    Airoldi, A.
    Quaglia, M.
    Ronco, C.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2020, 20 : 452 - 452
  • [7] Relationship between Estimated Glomerular Filtration Rate and Cardiovascular Mortality in a Japanese Cohort with Long-Term Follow-Up
    Nagai, Kei
    Sairenchi, Toshimi
    Irie, Fujiko
    Watanabe, Hiroshi
    Ota, Hitoshi
    Yamagata, Kunihiro
    [J]. PLOS ONE, 2016, 11 (06):
  • [8] Proteinuria Decreased the Estimated Glomerular Filtration Rate in Diabetic Patients: 12 Year Follow-Up Study
    Soejima, Hirofumi
    Morimoto, Takeshi
    Okada, Sadanori
    Matsumoto, Chisa
    Nakayama, Masafumi
    Jinnouchi, Hideaki
    Waki, Masako
    Masuda, Izuru
    Saito, Yoshihiko
    Ogawa, Hisao
    [J]. CIRCULATION, 2019, 140
  • [9] Longitudinal Trajectories of Estimated Glomerular Filtration Rate in a European Population of Living Kidney Donors
    Almeida, Manuela
    Reis Pereira, Pedro
    Silvano, Jose
    Ribeiro, Catarina
    Pedroso, Sofia
    Tafulo, Sandra
    Martins, La Salete
    Silva Ramos, Miguel
    Malheiro, Jorge
    [J]. TRANSPLANT INTERNATIONAL, 2024, 37
  • [10] Stabilization of estimated glomerular filtration rate in kidney transplantation from deceased donors with acute kidney injuries
    Punlop Wiwattanathum
    Atiporn Ingsathit
    Surasak Kantachuvesiri
    Nuttapon Arpornsujaritkun
    Wiwat Tirapanich
    Vasant Sumethkul
    [J]. World Journal of Transplantation, 2016, (04) : 712 - 718