The glucose metabolic reprogramming in hepatitis B virus infection and hepatitis B virus associated diseases

被引:0
|
作者
Wang, Hangle [1 ]
Zhang, Jun [1 ,2 ]
机构
[1] Peking Univ, Hlth Sci Ctr, Sch Basic Med Sci, Dept Immunol,Minist Hlth,NHC Key Lab Med Immunol, Beijing, Peoples R China
[2] Peking Univ, Hlth Sci Ctr, Sch Basic Med Sci, Dept Immunol,Minist Hlth,NHC Key Lab Med Immunol, Beijing 100191, Peoples R China
基金
中国国家自然科学基金;
关键词
Cirrhosis; Glucose metabolism; Hepatitis B virus; Hepatocellular carcinoma; Immune escape; HEPATOCELLULAR-CARCINOMA; REQUIREMENTS; ACTIVATION; CURCUMIN; PATHWAY; RISK;
D O I
10.1111/jgh.16340
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Hepatitis B virus (HBV) infection is closely related to viral hepatitis, liver cirrhosis, and hepatocellular carcinoma. HBV infection can reprogram metabolism processes of the host cells including glucose metabolism. The aberrant glucose metabolism may aid in viral infection and immune escape and may contribute to liver associated pathology. In this review, we discussed the interplay between HBV infection and glucose metabolism, which may provide new insights into HBV infection and pathology, novel intervention targets for HBV-related diseases. Glucose metabolic reprogramming pathways in the hepatocyte regulated by HBV. The molecules associated with different pathways are shown in different background colors.image
引用
收藏
页码:1886 / 1891
页数:6
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