Luspatercept Versus Epoetin Alfa for Treatment (Tx) of Anemia in Erythropoiesis-Stimulating Agent (ESA)-Naive Lower-Risk Myelodysplastic Syndromes (LR-MDS) Patients (pts) Requiring RBC Transfusions (RBCT): Data from the Phase 3 COMMANDS Study

被引：0

作者：

Platzbecker, U. ^{[1
]}

Della Porta, M. G. ^{[2
,3
]}

Santini, V. ^{[4
]}

Zeidan, A. M. ^{[5
,6
]}

Fenaux, P. ^{[7
]}

Komrokji, R. S. ^{[8
]}

Shortt, J. ^{[9
,10
]}

Valcarcel, D. ^{[11
]}

Jonasova, A. ^{[12
]}

Dimicoli-Salazar, S. ^{[13
]}

Tiong, I. S. ^{[14
]}

Lin, C. -C. ^{[15
]}

Li, J. ^{[16
]}

Zhang, J. ^{[16
]}

Giuseppi, A. C. ^{[16
]}

Kreitz, S. ^{[17
]}

Pozharskaya, V. ^{[16
]}

Keeperman, K. L. ^{[16
]}

Rose, S. ^{[16
]}

Shetty, J. K. ^{[17
]}

Hayati, S. ^{[16
]}

Vodala, S. ^{[16
]}

Degulys, A. ^{[18
,19
]}

Paolini, S. ^{[20
]}

Cluzeau, T. ^{[21
]}

Garcia-Manero, G. ^{[22
]}

机构：

[1] Univ Hosp Leipzig, Med Clin & Policlin 1, Hematol & Cellular Therapy, Leipzig, Germany

[2] IRCCS Humanitas Res Hosp, Ctr Canc, Milan, Italy

[3] Humanitas Univ, Dept Biomed Sci, Milan, Italy

[4] Univ Florence, MDS Unit, AOUC, Hematol, Florence, Italy

[5] Yale Univ, Yale Sch Med, New Haven, CT USA

[6] Yale Canc Ctr, Dept Internal Med, New Haven, CT USA

[7] Univ Paris 07, Serv Hematol Seniors, Hop St Louis, Paris, France

[8] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

[9] Monash Univ, Melbourne, Vic, Australia

[10] Monash Hlth, Melbourne, Vic, Australia

[11] Hosp Univ Vall dHebron, Barcelona, Spain

[12] Charles Univ Prague, Gen Univ Hosp, Dept Med Hematol, Prague, Czech Republic

[13] Hop Haut Leveque, Ctr Hosp Univ Bordeaux, Bordeaux, France

[14] The Alfred, Malignant Haematol & Stem Cell Transplantat, Melbourne, Vic, Australia

[15] Natl Taiwan Univ Hosp, Dept Lab Med, Taipei, Taiwan

[16] Bristol Myers Squibb, Princeton, NJ USA

[17] Celgene Int Sarl, Boudry, Switzerland

[18] Vilnius Univ Hosp Santaros Klinikos, Hematol Oncol & Transfus Med Ctr, Vilnius, Lithuania

[19] Vilnius Univ, Inst Clin Med, Fac Med, Vilnius, Lithuania

[20] IRCCS Univ Hosp Bologna, Seragnoli Inst Hematol, Bologna, Italy

[21] Univ Cote dAzur, CHU Nice, Dept Hematol Clin, Nice, France

[22] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX USA

来源：

ONCOLOGY RESEARCH AND TREATMENT | 2023年 / 46卷

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

V61

引用

页码：16 / 17

页数：2

共 35 条

[1] Luspatercept versus epoetin alfa (EA) for treatment (tx) of anemia in ESA-naive lower-risk myelodysplastic syndromes (LR-MDS) patients (pts) requiring RBC transfusions (RBCT): data from the phase 3 COMMANDS study
Platzbecker, Uwe
Porta, Matteo Giovanni
Santini, Valeria
Zeidan, Amer M.
Fenaux, Pierre
Komrokji, Rami S.
Shortt, Jake
Valcarcel, David
Jonasova, Anna
Dimicoli-Salazar, Sophie
Tiong, Ing Soo
Lin, Chien-Chin
Li, Jiahui
Zhang, Jennie
Giuseppi, Ana Carolina
Kreitz, Sandra
Pozharskaya, Veronika
Keeperman, Karen L.
Rose, Shelonitda
Shetty, Jeevan K.
Hayati, Sheida
Vodala, Sadanand
Degulys, Andrius
Paolini, Stefania
Cluzeau, Thomas
Garcia-Manero, Guillermo
ONCOLOGY RESEARCH AND TREATMENT, 2024, 47 : 116 - 116
[2] Luspatercept Versus Epoetin Alfa (EA) for Treatment of Anemia in Patients With Erythropoiesis-Stimulating Agent (ESA)-Naive Lower-Risk Myelodysplastic Syndromes (LR-MDS) Requiring Red Blood Cell (RBC) Transfusions: Data from the Phase III COMMANDS Study
Garcia-Manero, Guillermo
Platzbecker, Uwe
Santini, Valeria
Zeidan, Amer M.
Fenaux, Pierre
Komrokji, Rami S.
Shortt, Jake
Valcarcel, David
Jonasova, Anna
Dimicoli-Salazar, Sophie
Tiong, Ing Soo
Lin, Chien-Chin
Li, Jiahui
Zhang, Jennie
Giuseppi, Ana Carolina
Kreitz, Sandra
Pozharskaya, Veronika
Keeperman, Karen L.
Rose, Shelonitda
Shetty, Jeevan K.
Hayati, Sheida
Vodala, Sadanand
Degulys, Andrius
Paolini, Stefania
Cluzeau, Thomas
Della Porta, Matteo
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2023, 23 : S355 - S356
[3] Efficacy and Safety of Luspatercept Versus Epoetin Alfa in Erythropoiesis-Stimulating Agent (ESA)-Naive Patients (Pts) with Transfusion-Dependent (TD) Lower-Risk Myelodysplastic Syndromes (LR-MDS): Full Analysis of the COMMANDS Trial
Garcia-Manero, Guillermo
Platzbecker, Uwe
Santini, Valeria
Zeidan, Amer M.
Fenaux, Pierre
Komrokji, Rami S.
Shortt, Jake
Valcarcel, David
Jonasova, Anna
Dimicoli-Salazar, Sophie
Tiong, Ing Soo
Lin, Chien-Chin
Li, Jiahui
Zhang, Jennie
Giuseppi, Ana Carolina
Kreitz, Sandra
Pozharskaya, Veronika
Keeperman, Karen L.
Rose, Shelonitda
Prebet, Thomas
Degulys, Andrius
Paolini, Stefania
Cluzeau, Thomas
Della Porta, Matteo Giovanni
BLOOD, 2023, 142
[4] Efficacy and safety of luspatercept versus epoetin alfa (EA) in erythropoiesis-stimulating agent (ESA)-naive patients (pts) with transfusion-dependent (TD) lower-risk myelodysplastic syndromes (LR-MDS): full analysis of the COMMANDS trial
Platzbecker, Uwe
Garcia-Manero, Guillermo
Santini, Valeria
Zeidan, Amer M.
Fenaux, Pierre
Komrokji, Rami S.
Shortt, Jake
Valcarcel, David
Jonasova, Anna
Dimicoli-Salazar, Sophie
Tiong, Ing Soo
Lin, Chien-Chin
Li, Jiahui
Zhang, Jennie
Giuseppi, Ana Carolina
Kreitz, Sandra
Pozharskaya, Veronika
Keeperman, Karen L.
Rose, Shelonitda
Prebet, Thomas
Degulys, Andrius
Paolini, Stefania
Cluzeau, Thomas
Porta, Matteo Giovanni
ONCOLOGY RESEARCH AND TREATMENT, 2024, 47 : 243 - 243
[5] Efficacy and safety results from the COMMANDS trial: A phase 3 study evaluating luspatercept vs epoetin alfa in erythropoiesis-stimulating agent (ESA)-naive transfusion-dependent (TD) patients (pts) with lower-risk myelodysplastic syndromes (LR-MDS).
Garcia-Manero, Guillermo
Platzbecker, Uwe
Santini, Valeria
Zeidan, Amer Methqal
Fenaux, Pierre
Komrokji, Rami S.
Shortt, Jake
Valcarcel, David
Jonasova, Anna
Dimicoli-Salazar, Sophie
Tiong, Ing Soo
Lin, Chien-Chin
Li, Jiahui
Kreitz, Sandra
Pozharskaya, Veronika
Shetty, Jeevan K.
Degulys, Andrius
Finelli, Carlo
Cluzeau, Thomas
Della Porta, Matteo Giovanni
JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)
[6] Patient-Reported Outcomes (PRO) of Luspatercept Versus Epoetin Alfa in Erythropoiesis-Stimulating Agent (ESA)-Naive, Transfusion-Dependent (TD), Lower-Risk Myelodysplastic Syndromes (LR-MDS): Results from the Phase 3 COMMANDS Study
Oliva, Esther Natalie
Platzbecker, Uwe
Della Porta, Matteo Giovanni
Garcia-Manero, Guillermo
Santini, Valeria
Fenaux, Pierre
Shortt, Jake
Komrokji, Rami S.
Pelligra, Christopher
Guo, Shien
Lord-Bessen, Jennifer
Xiao, Hong
Yucel, Aylin
Miteva, Dimana
Rose, Shelonitda
Kreitz, Sandra
Sekeres, Mikkael A.
Zeidan, Amer M.
BLOOD, 2023, 142
[7] Long-Term Evaluation of Luspatercept in Erythropoiesis-Stimulating Agent (ESA)Intolerant/Refractory Patients (pts) with Lower-Risk Myelodysplastic Syndromes (LR-MDS) in the Phase 3 MEDALIST Study
Santini, Valeria
Komrokji, Rami S.
Garcia-Manero, Guillermo
Buckstein, Rena
Oliva, Esther Natalie
Keeperman, Karen L.
Rose, Shelonitda
Giuseppi, Ana Carolina
Vilmont, Valerie
Lai, Yinzhi
Miteva, Dimana
Aggarwal, Barkha
Platzbecker, Uwe
Fenaux, Pierre
Zeidan, Amer M.
BLOOD, 2023, 142
[8] Real-world erythropoiesis-stimulating agent (ESA) treatment patterns and outcomes among US patients with lower-risk myelodysplastic syndromes (LR-MDS).
Mukherjee, Sudipto
Savill, Kristin M. Zimmerman
Gajra, Ajeet
Kish, Jonathan K.
Brown-Bickerstaff, Cherrishe
Gentile, Danielle
Falkenstein, Angelica
Miller, Talia
Laney, Jalyna R.
McBride, Ali
JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)
[9] The ELEMENT-MDS Trial: A Phase 3 Randomized Study Evaluating Luspatercept Versus Epoetin Alfa in Erythropoiesis-Stimulating Agent-Naive, Non-Transfusion-Dependent, Lower-Risk Myelodysplastic Syndromes
Zeidan, Amer M.
Komrokji, Rami S.
Buckstein, Rena
Santini, Valeria
Rose, Shelonitda
Malini, Priya
Lew, Glen
Aggarwal, Dimple
Keeperman, Karen L.
Jiang, Huijing
Giuseppi, Ana Carolina
Zhang, Jennie
Cluzeau, Thomas
Shortt, Jake
Platzbecker, Uwe
BLOOD, 2023, 142
[10] Reduction of Transfusion Burden (TB), Hemoglobin Increase, and Dose Titration in the COMMANDS Study of Luspatercept Versus Epoetin Alfa (EA) in Erythropoietin-Stimulating Agent (ESA)-Naive Patients With Transfusion-Dependent (TD) Lower-Risk Myelodysplastic Syndromes (LR-MDS)
Komrokji, Rami S.
Platzbecker, Uwe
Della Porta, Matteo
Santini, Valeria
Garcia-Manero, Guillermo
Li, Jiahui
Zhang, Jennie
Giuseppi, Ana Carolina
Kreitz, Sandra
Pozharskaya, Veronika
Keeperman, Karen L.
Rose, Shelonitda
Hughes, Christina
Valcarcel, David
Fenaux, Pierre
Shortt, Jake
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2023, 23 : S358 - S359

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