Tumor-Intrinsic and -Extrinsic Mechanisms of MRTF-Dependent Regulation of Bone Colonization by Breast Cancer Cells

被引:0
|
作者
Gau, David M. [1 ]
Sun, Quanhong [2 ]
Chawla, Pooja [1 ]
Elder, Ian [1 ]
Joy, Marion [3 ]
Lucas, Peter C. [4 ,5 ]
Boone, David N. [6 ]
Galson, Deborah L. [7 ,8 ,9 ]
Roy, Partha [10 ]
机构
[1] Univ Pittsburgh, Swanson Sch Engn, Dept Bioengn, Pittsburgh, PA USA
[2] Univ Pittsburgh, Dept Med, Div Hematol Oncol, Pittsburgh, PA 15260 USA
[3] Univ Pittsburgh, Med Ctr, Pittsburgh, PA USA
[4] Univ Pittsburgh, Dept Pathol, Sch Med, UPMC Hillman Canc Ctr, Pittsburgh, PA USA
[5] Univ Pittsburgh, Sch Med, Dept Pediat, UPMC Hillman Canc Ctr, Pittsburgh, PA USA
[6] Univ Pittsburgh, Sch Med, Dept Biomed Informat, UPMC Hillman Canc Ctr, Pittsburgh, PA USA
[7] Univ Pittsburgh, McGowan Inst Regenerat Med, Sch Med, UPMC Hillman Canc Ctr,Div Hematol Oncol,Dept Med, Pittsburgh, PA USA
[8] Univ Pittsburgh, McGowan Inst Regenerat Med, Sch Med, UPMC Hillman Canc Ctr,Div Hematol Oncol,Dept Micr, Pittsburgh, PA USA
[9] Univ Pittsburgh, McGowan Inst Regenerat Med, Sch Med, UPMC Hillman Canc Ctr,Div Hematol Oncol,Dept Mol, Pittsburgh, PA USA
[10] Univ Pittsburgh, Swanson Sch Engn, Sch Med, Dept Pathol,UPMC Hillman Canc Ctr, Pittsburgh, PA USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
SUN-161
引用
收藏
页码:208 / 208
页数:1
相关论文
共 50 条
  • [1] Resistance Mechanisms to Immune-Checkpoint Blockade in Cancer: Tumor-Intrinsic and -Extrinsic Factors
    Pitt, Jonathan M.
    Vetizou, Marie
    Daillere, Romain
    Roberti, Maria Paula
    Yamazaki, Takahiro
    Routy, Bertrand
    Lepage, Patricia
    Boneca, Ivo Gomperts
    Chamaillard, Mathias
    Kroemer, Guido
    Zitvogel, Laurence
    [J]. IMMUNITY, 2016, 44 (06) : 1255 - 1269
  • [2] MRTF/SRF dependent transcriptional regulation of TAZ in breast cancer cells
    Liu, Chen-Ying
    Chan, Siew Wee
    Guo, Fusheng
    Toloczko, Aleksandra
    Cui, Long
    Hong, Wanjin
    [J]. ONCOTARGET, 2016, 7 (12) : 13706 - 13716
  • [3] Mechanisms of breast cancer metastasis that are extrinsic to tumor cells
    Eyob, Henok
    Kretschmann, Kelsi L.
    Welm, Alana L.
    [J]. CLINICAL & EXPERIMENTAL METASTASIS, 2011, 28 (02) : 255 - 255
  • [4] Ovarian tumor-intrinsic FAK-dependent regulation of the matrisome
    Ojalill, Marjaana
    Zhang, Joanna
    Suwal, Ujjwal
    Rappu, Pekka
    Heino, Jyrki
    Connolly, Denise C.
    Stupack, Dwayne G.
    Schlaepfer, David D.
    [J]. CANCER RESEARCH, 2023, 83 (07)
  • [5] Obesity and Cancer Metabolism: A Perspective on Interacting Tumor-Intrinsic and Extrinsic Factors.
    Doerstling, Steven S.
    O'Flanagan, Ciara H.
    Hursting, Stephen D.
    [J]. FRONTIERS IN ONCOLOGY, 2017, 7
  • [6] Cancer Stem Cells in Hepatocellular Carcinoma: Intrinsic and Extrinsic Molecular Mechanisms in Stemness Regulation
    Fang, Xiaona
    Yan, Qian
    Liu, Shan
    Guan, Xin-Yuan
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (20)
  • [7] Lipocalin-2 promotes breast cancer metastasis via tumor cell intrinsic and extrinsic mechanisms
    Gamez, Joshua
    Sanchez, Francesca
    Ortiz-Soto, Gabriela
    Cox, Jane
    Gerami, Amir
    Kelber, Jonathan A.
    [J]. CANCER RESEARCH, 2024, 84 (06)
  • [8] Tumor-intrinsic IRF5 reprograms the tumor immune microenvironment to inhibit breast cancer metastasis
    Barnes, Betsy J.
    Li, Dan
    Somerville, Carter
    Castro-Piedras, Isabel
    Pruitt, Kevin
    [J]. JOURNAL OF IMMUNOLOGY, 2021, 206
  • [9] Extrinsic and Intrinsic Force Regulation of Breast Cancer Progression and Treatment.
    Weaver, V. M. M.
    [J]. CANCER RESEARCH, 2011, 71
  • [10] MRTF-SRF interaction promotes bone metastasis of breast cancer cells
    Chawla, P.
    Gau, D. M.
    Sun, Q.
    Boone, D.
    Galson, D.
    Roy, P.
    [J]. MOLECULAR BIOLOGY OF THE CELL, 2023, 34 (02) : 992 - 993