Treatment with Exosomes Derived from Mesenchymal Stem Cells: A New Window of Healing Science in Regenerative Medicine

被引:2
|
作者
Hormozi, Arezoo [1 ]
Hasanzadeh, Sajedeh [1 ]
Ebrahimi, Faezeh [1 ]
Daei, Narges [1 ]
Hajimortezayi, Zahra [1 ]
Mehdizadeh, Amir [2 ]
Zamani, Majid [3 ]
机构
[1] Gonabad Univ Med Sci, Student Res Comm, Gonabad, Iran
[2] Tabriz Univ Med Sci, Hematol & Oncol Res Ctr, Tabriz, Iran
[3] Tarbiat Modares Univ, Fac Med Sci, Dept Hematol, Tehran, Iran
关键词
Mesenchymal stem cells; exosomes; Micro-RNA; clinical application; therapy; extracellular vesicles; microvesicles; EXTRACELLULAR VESICLES; OSTEOARTHRITIS; STRATEGY; DISEASES; BIOLOGY; STORAGE;
D O I
10.2174/1574888X18666230824165014
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Many studies have been conducted on the potential applications of mesenchymal stem cells (MSCs) over recent years due to their growing importance in regenerative medicine. Exosomes are considered cargos capable of transporting proteins, peptides, lipids, mRNAs, and growth factors. MSCs-derived exosomes are also involved in the prevention or treatment of a variety of diseases, including cardiovascular diseases, neurological diseases, skin disorders, lung diseases, osteoarthritis, damaged tissue repair, and other diseases. This review attempted to summarize the importance of employing MSCs in regenerative medicine by gathering and evaluating information from current literature. The role of MSCs and the potential applications of MSCs-derived exosomes have also been discussed.
引用
收藏
页码:879 / 893
页数:15
相关论文
共 50 条
  • [1] Potential applications of mesenchymal stem cells and their derived exosomes in regenerative medicine
    Adelipour, Maryam
    Lubman, David M.
    Kim, Jeongkwon
    EXPERT OPINION ON BIOLOGICAL THERAPY, 2023, 23 (06) : 491 - 507
  • [2] The Opportunities and Challenges of Mesenchymal Stem Cells-Derived Exosomes in Theranostics and Regenerative Medicine
    Yadav, Sachin
    Maity, Pritiprasanna
    Kapat, Kausik
    CELLS, 2024, 13 (23)
  • [3] Mesenchymal Stem Cell-Derived Exosomes: Applications in Regenerative Medicine
    Hade, Mangesh D.
    Suire, Caitlin N.
    Suo, Zucai
    CELLS, 2021, 10 (08)
  • [4] Exosomes derived from mesenchymal stem cells: Heralding a new treatment for periodontitis?
    Mousavi, Elnaz
    Khosravi, Armin
    Sedigh, Somaye Salari
    Mayanei, Sayad Ayub Tabatabaei
    Banakar, Morteza
    Karimzadeh, Moslem
    Fathi, Amirhossein
    TISSUE & CELL, 2023, 82
  • [5] Mesenchymal stem cells derived exosomes: an advanced regenerative medicine strategies for treatment of perianal fistula in inflammatory bowel disease?
    Cheng, F.
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2024, 39 (01) : 210 - 210
  • [6] Recent advances in the application of engineered exosomes from mesenchymal stem cells for regenerative medicine
    Abbasi, Reza
    Alamdari-Mahd, Ghazal
    Maleki-Kakelar, Hadi
    Momen-Mesgin, Razieh
    Ahmadi, Mahdi
    Sharafkhani, Mohaddeseh
    Rezaie, Jafar
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2025, 989
  • [7] Emerging Role of Mesenchymal Stem Cell-derived Exosomes in Regenerative Medicine
    Zhao, Ting
    Sun, Feng
    Liu, Jinwen
    Ding, Tianyan
    She, Jie
    Mao, Fei
    Xu, Wenrong
    Qian, Hui
    Yan, Yongmin
    CURRENT STEM CELL RESEARCH & THERAPY, 2019, 14 (06) : 482 - 494
  • [8] Role of Mesenchymal Stem Cells Derived Exosomes and Its Regenerative Potential
    Ravi, Padma Kanchi
    Balakrishna, Janardhana Papayya
    Dhawale, Lavina
    ENTOMOLOGY AND APPLIED SCIENCE LETTERS, 2020, 7 (02): : 11 - 19
  • [9] Application of mesenchymal stem cells derived from human pluripotent stem cells in regenerative medicine
    Liu, Tong-Ming
    WORLD JOURNAL OF STEM CELLS, 2021, 13 (12): : 1826 - 1844
  • [10] Extracellular Vesicles Derived From Mesenchymal Stem Cells (MSC) in Regenerative Medicine: Applications in Skin Wound Healing
    Casado-Diaz, Antonio
    Quesada-Gomez, Jose Manuel
    Dorado, Gabriel
    FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2020, 8