Computational analysis of patient-specific pulsatile blood flow: The influence of non-Newtonian models on wall shear stress assessment

被引:2
|
作者
Singh, Damini [1 ]
Singh, Sarita [1 ]
机构
[1] Doon Univ, Sch Phys Sci, Dept Math, Dehra Dun 248001, Uttarakhand, India
关键词
HUMAN CAROTID BIFURCATION; NUMERICAL-SIMULATION; CORONARY-ARTERIES; MECHANICS; VESSEL; VISCOSITY;
D O I
10.1063/5.0180474
中图分类号
O3 [力学];
学科分类号
08 ; 0801 ;
摘要
Blood is a sophisticated biological fluid with components like erythrocytes that give it non-Newtonian behavior. Hemodynamic factors such as velocity magnitude, pressure, and wall shear stress descriptors are the most important factors in the development of atherosclerosis. The wall shear stress descriptors are regulated not only by flow geometry but also by blood rheological properties. In the current study, we carried out a numerical analysis of the non-Newtonian pulsatile blood flow while taking into account a patient-specific geometry and transient boundary conditions. Non-Newtonian blood flow is modeled using the four non-Newtonian models: the power-law model, the Carreau model, the Casson model, and the Quemada model, and compared with the Newtonian model. Streamline analysis vividly illustrates velocity patterns, revealing the presence of recirculation zones near sinus regions. The study suggests the significance of selecting appropriate viscosity models for accurate assessments, particularly in regions with low time-average wall shear stress values, such as those associated with atherosclerotic plaques. The differences in the time-averaged wall shear stress between the four non-Newtonian models were found to be the highest in the Quemada model. The study concluded that the non-Newtonian model is required when the focus is on the low-time-averaged wall shear stress area.
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页数:16
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