Immunohistochemical Studies of the Expression of Matrix Metalloproteinase-2 and Metalloproteinase-9 in Human Prostate Cancer

被引：0
|
作者：
曾汉青
肖亚军
鲁功成
陈勇
机构：
[1] Tongji Medical College
[2] Department of Urology
[3] Department of Urology Union Hospital
[4] Wuhan 430071
[5] Wuhan University
[6] Wuhan 430022
[7] Huazhong University of Science and Technology
[8] Zhongnan Hospital
来源：
Current Medical Science | 2003年 / 04期
关键词：
prostate cancer; matrix metalloproteinase 2; matrix metalloproteinase 9; immunohistochemistry;
D O I：
暂无
中图分类号：
R737.25 [前列腺肿瘤];
学科分类号：
100214 ;
摘要：
To study the expression of matrix metalloproteinase 2 and 9 in human prostate cancer, matrix metalloproteinase 2 and 9 were immunohistochemically detected in tissues of prostate cancer and benign prostatic hyperplasia (BPH). Our results showed that matrix metalloproteinase 2 and 9 levels in prostate cancer were much higher than those in tissues of BPH, with the cancer invasion being positively correlated with the expression of the metalloproteinases. It is concluded that matrix metalloproteinase 2 and 9 are better molecular markers, which are of help in the diagnosis and prediction of prognosis of prostate cancer.
引用
收藏
页码：373 / 374 +379
页数：3
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