Recent advances in electrogenerated chemiluminescence biosensing methods for pharmaceuticals

被引：1

作者：

Yu Zhang ^{[1
]}

Rui Zhang ^{[2
]}

Xiaolin Yang ^{[3
]}

Honglan Qi ^{[3
]}

Chengxiao Zhang ^{[3
]}

机构：

[1] Medpace Bioanalytical Laboratories

[2] School of Informatics, Computing, and Engineering, Indiana University

[3] Key Laboratory of Analytical Chemistry for Life Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University

来源：

Journal of Pharmaceutical Analysis | 2019年 / 9卷 / 01期

关键词：

Electrogenerated chemiluminescence; Pharmaceutical analysis; Immunoassay; Biosensors;

D O I：

暂无

中图分类号：

O657.1 [电化学分析法]; TQ460.72 [];

学科分类号：

070302 ; 081704 ; 100704 ;

摘要：

Electrogenerated chemiluminescence(electrochemiluminescence, ECL) generates species at electrode surfaces, which undergoes electron-transfer reactions and forms excited states to emit light. It has become a very powerful analytical technique and has been widely used in such as clinical testing, biowarfare agent detection, and pharmaceutical analysis. This review focuses on the current trends of molecular recognition-based biosensing methods for pharmaceutical analysis since 2010. It introduces a background of ECL and presents the recent ECL developments in ECL immunoassay(ECLIA), immunosensors, enzyme-based biosensors, aptamer-based biosensors, and molecularly imprinted polymers(MIP)-based sensors. At last, the future perspective for these analytical methods is briefly discussed.

引用

页码：9 / 19

页数：11

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