Three new secoiridoid glycosides from the flower buds of Lonicera japonica

被引：0
|
作者：
YANG Ran [1 ]
HAO Hao [2 ]
LI Jia [1 ]
XUAN Jing [1 ]
XIA Ming-Feng [2 ]
ZHANG Yong-Qing [1 ]
机构：
[1] Key laboratory of Natural Pharmaceutical Chemistry, Shandong University of Traditional Chinese Medicine
[2] Key laboratory of Pharmacology, Shandong University of Traditional Chinese Medicine
来源：
Chinese Journal of Natural Medicines | 2020年 / 18卷 / 01期
关键词：
Lonicera japonica; Secoiridoid glycosides; Spectroscopic analysis; Anti-inflammatory activity;
D O I：
暂无
中图分类号：
R284 [中药化学];
学科分类号：
1008 ;
摘要：
Three new secoiridoid glycosides, named lonijapoglycol A（1）, aldosecolohanin C（2） and aldosecolohanin B（3）, together with three known ones（4–6）, have been isolated from the flower the buds of Lonicera japonica. All the structures were identified by spectroscopic analyses. Lonijapoglycol A（1） expressed significant anti-inflammatory activity to inhibit the release of β-glucuronidase induced by platelet-activating factor in rat polymorphonuclear leukocytes with an IC;value of 3.76 μmol·L;.
引用
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页码：70 / 74
页数：5
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