Nanoengineering of amino-functionalized mesoporous silica nanospheres as nanoreactors

Selective functionalization of mesoporous silica nanospheres（MSNs） is crucial for nanoengineering of MSNs.Herein, we have combined "surface-protected etching strategy" and "cationic surfactant assisted etching strategy" to prepare functionalized MSNs with externally attached amino groups. The externally attached NH;groups endow the catalysts with excellent catalytic performance for nitroaldol reaction between nitromethane and benzaldehyde. In addition, those NH;-MSNs can also be used to support gold nanoparticles, which display very good catalytic performance for reduction of 4-nitrophenol. It can be envisioned that the synthesis protocol developed in this work could also be extended to nanoengineered MSNs, which provides opportunities for nanoreactors design.