Polyphyllin D induces G2/M Cell Cycle Arrest via Dysfunction of Cholesterol Biosynthesis in Liver Cancer Cells

被引:0
|
作者
CHEN Yan Yan [1 ]
REN Cai Fang [1 ]
WEN Shi Yuan [2 ]
机构
[1] School of Medicine, Jiangsu University
[2] College of Basic Medical Sciences,Shanxi Medical University
基金
山西省青年科学基金;
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D O I
暂无
中图分类号
R735.7 [肝肿瘤];
学科分类号
100214 ;
摘要
Liver cancer is a frequently occurring malignancy with a poor prognosis and a high mortality rate and is the second leading cause of cancer-related deaths[1]. Many chemotherapeutic drugs are extensively used to treat liver cancer, such as doxorubicin and cisplatin. However, these drugs have shown poor treatment effects in clinical trials because of acquired resistance and the high heterogeneity of liver cancer[2]. Therefore,
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页码:94 / 98
页数:5
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