miR-181b在恶性肿瘤中的研究进展

被引：2
|
作者：
崔建琦
赵艳滨
机构：
[1] 哈尔滨医科大学附属肿瘤医院内五科
来源：
现代肿瘤医学 | 2019年 / 27卷 / 18期
关键词：
miR-181b; 恶性肿瘤; 研究进展;
D O I：
暂无
中图分类号：
R730.2 [肿瘤病理学、病因学];
学科分类号：
摘要：
miRNA是一种存在于真核生物中的内源性非编码短链RNA,具有极其复杂的调控机制,可对肿瘤的发生发展起到广泛调节的作用,即可作为致瘤因子,亦可作为抑瘤因子。随着对miRNA研究的不断深入,miR-181b在恶性肿瘤中的表达已成为医学领域关注的热点问题。研究表明,miR-181b存在多个靶点,每个靶基因又参与调控多种细胞功能,从而在恶性肿瘤的增殖、凋亡、侵袭、转移及耐药等过程中起到错综复杂的作用。而且它还对肿瘤的早期诊断有预测作用。本文就miR-181b在恶性肿瘤中的研究进展作一综述。
引用
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页码：3327 / 3329
页数：3
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