Removal of Endotoxin from Human Serum Albumin Solutions by Hydrophobic and Cationic Charged Membrane

被引：0
|
作者：
Gui Lin WEI~1
Zhen Hua SHAN~1
Ming Chen PAN~2
Zhi Hong GAO~2 (1Dalian Institute of Chemical Physics. Chinese Academy of Sciences. Dalian 1 16012 2 Dalian Medical University 1st Teaching Hospital)
机构：
来源：
ChineseChemicalLetters | 2000年 / 04期
基金：
中国国家自然科学基金;
关键词：
Hydrophobic and cationic charged membrane. endotoxin removal;
D O I：
暂无
中图分类号：
Q936 [微生物生物化学];
学科分类号：
071010 ;
摘要：
A novel matrix of macropore cellulose membrane was prepared by chemical graft, and immobilized the cationic charged groups as affinity ligands. The prepared membrane can be used for the removal of endotoxin from. human serum albumin (HSA) solutions. With a cartridge of 20 sheets affinity membrane of 47 mm diameter, the endotoxin level in HSA solution can be reduced to 0.027 eu/mL. Recovery of HSA was over 95%.
引用
收藏
页码：357 / 360
页数：4
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