IA-2及IA-2β与1型糖尿病

[1] Honeyman MC,Stone NL,Harrison LC.T-cell epitopes in type 1 diabetes autoantigen tyrosine phosphatase IA-2: potential for mimicry with rotavirus and other environmental agents〔J〕. Molecular Medicine . 1998

[2] Weist-Ladenburger U,Hartmann R,Hartmann U,et al.Combined analysis and single-step detection of GAD65 and IA-2 autoantibodies in IDDM can replace the histochemical islet cell antibody test〔J〕. Diabetes . 1997

[3] Sanjeevi CB,Hagopian WA,Landin-Olsson M,et al.Association between autoantibody markers and subtypes of DR4 and DR4-DQ in Swedish children with insulin-dependent diabetes reveals closer association of tyrosine pyrophosphatase autoimmunity with DR4 than DR8〔J〕. Tissue Antigens . 1998

[4] Lu J,Li Q,Xie H,et al.Identification of a second transmembrane protein tyrosine phosphatase, IA-2 beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37KDa tryptic fragment〔J〕. Proceedings of the National Academy of Sciences of the United States of America . 1996

[5] Verge CF,Gianani R,Kawasaki E,et al.Prediction of type 1 diabetes in first-degree relatives using a combination of insulin, GAD and ICA512 bdc/IA-2 autoantibodies 〔J〕. Diabetes . 1996

[6] Lan MS,Lu J,Goto Y,et al.Molecular cloning and identification of a receptor-type protein tyrosine phosphatase, IA-2, from human insulinoma〔J〕. DNA and Cell Biology . 1994

[7] Whittingham S,Byron SL,Tuomilehto J,et al.Autoantibodies associated with presymptomatic insulin-dependent diabetes mellitus in women〔J〕. Diabetic Medicine . 1997

[8] Kawasaki E,Hutton JC,Eisenbarth GS,et al.Molecular cloning and characterization of the human transmembrane protein tyrosine phosphatase homologue, phogrin, an autoantigen of type 1 diabetes 〔J〕. Biochemical and Biophysical Research Communications . 1996

[9] Dittler J,Seidel D,Schenker M,et al.GAD IA2-combi determination as first-line screening for improved prediction of typeⅠdiabetes in relatives〔J〕. Diabetes . 1998

[10] Wasmeier C,Hutton JC.Molecular cloning of phogrin, a protein-tyrosine phosphatase homologue localized to insulin secretory granule membranes〔J〕. Journal of Biological Chemistry . 1996

[1] Honeyman MC,Stone NL,Harrison LC.T-cell epitopes in type 1 diabetes autoantigen tyrosine phosphatase IA-2: potential for mimicry with rotavirus and other environmental agents〔J〕. Molecular Medicine . 1998

[2] Weist-Ladenburger U,Hartmann R,Hartmann U,et al.Combined analysis and single-step detection of GAD65 and IA-2 autoantibodies in IDDM can replace the histochemical islet cell antibody test〔J〕. Diabetes . 1997

[3] Sanjeevi CB,Hagopian WA,Landin-Olsson M,et al.Association between autoantibody markers and subtypes of DR4 and DR4-DQ in Swedish children with insulin-dependent diabetes reveals closer association of tyrosine pyrophosphatase autoimmunity with DR4 than DR8〔J〕. Tissue Antigens . 1998

[4] Lu J,Li Q,Xie H,et al.Identification of a second transmembrane protein tyrosine phosphatase, IA-2 beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37KDa tryptic fragment〔J〕. Proceedings of the National Academy of Sciences of the United States of America . 1996

[5] Verge CF,Gianani R,Kawasaki E,et al.Prediction of type 1 diabetes in first-degree relatives using a combination of insulin, GAD and ICA512 bdc/IA-2 autoantibodies 〔J〕. Diabetes . 1996

[6] Lan MS,Lu J,Goto Y,et al.Molecular cloning and identification of a receptor-type protein tyrosine phosphatase, IA-2, from human insulinoma〔J〕. DNA and Cell Biology . 1994

[7] Whittingham S,Byron SL,Tuomilehto J,et al.Autoantibodies associated with presymptomatic insulin-dependent diabetes mellitus in women〔J〕. Diabetic Medicine . 1997

[8] Kawasaki E,Hutton JC,Eisenbarth GS,et al.Molecular cloning and characterization of the human transmembrane protein tyrosine phosphatase homologue, phogrin, an autoantigen of type 1 diabetes 〔J〕. Biochemical and Biophysical Research Communications . 1996

[9] Dittler J,Seidel D,Schenker M,et al.GAD IA2-combi determination as first-line screening for improved prediction of typeⅠdiabetes in relatives〔J〕. Diabetes . 1998

[10] Wasmeier C,Hutton JC.Molecular cloning of phogrin, a protein-tyrosine phosphatase homologue localized to insulin secretory granule membranes〔J〕. Journal of Biological Chemistry . 1996