Biocatalytic synthesis of (R)-(-)-mandelic acid from racemic mandelonitrile by a newly isolated nitrilase-producer Alcaligenes sp. ECU0401

被引：11
|
作者：
Yu Cai He
机构：
来源：
Chinese Chemical Letters | 2007年 / 06期
关键词：
Mandelonitrile; Nitrilase; (R)-(-)-Mandelic acid; Screening; Alcaligenes sp. ECU0401;
D O I：
暂无
中图分类号：
TQ463.2 [];
学科分类号：
1007 ;
摘要：
By using acetonitrile as the sole nitrogen source, a microbial strain with high nitrilase activity, named as Alcaligenes sp. ECU0401, was newly isolated from soil, which could enantioselectively transform racemic mandelonitrile into (R)-(-)-mandelic acid, with an enantiomeric excess of >99.9%.
引用
收藏
页码：677 / 680
页数：4
相关论文
共 16 条
  • [1] Biocatalytic synthesis of (R)-(-)-mandelic acid from racemic mandelonitrile by a newly isolated nitrilase-producer Alcaligenes sp ECU0401
    He, Yu Cai
    Xu, Jian He
    Xu, Yi
    Ouyang, Li Ming
    Pan, Jiang
    [J]. CHINESE CHEMICAL LETTERS, 2007, 18 (06) : 677 - 680
  • [2] Biocatalytic synthesis of (R)-(-)-mandelic acid from racemic mandelonitrile by cetyltrimethylammonium bromide-permeabilized cells of Alcaligenes faecalis ECU0401
    He, Yu-Cai
    Zhang, Zhi-Jun
    Xu, Jian-He
    Liu, You-Yan
    [J]. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 2010, 37 (07) : 741 - 750
  • [3] Preparation of (R)-(−)-mandelic acid and its derivatives from racemates by enantioselective degradation with a newly isolated bacterial strain Alcaligenes sp. ECU0401
    Yu-Cai He
    Jian-He Xu
    Jiang Pan
    Li-Ming Ouyang
    Yi Xu
    [J]. Bioprocess and Biosystems Engineering, 2008, 31 : 445 - 451
  • [4] Cloning and biochemical properties of a highly thermostable and enantioselective nitrilase from Alcaligenes sp. ECU0401 and its potential for (R)-(−)-mandelic acid production
    Zhi-Jun Zhang
    Jian-He Xu
    Yu-Cai He
    Li-Ming Ouyang
    You-Yan Liu
    [J]. Bioprocess and Biosystems Engineering, 2011, 34 : 315 - 322
  • [5] Preparation of (R)-(-)-mandelic acid and its derivatives from racemates by enantioselective degradation with a newly isolated bacterial strain Alcaligenes sp ECU0401
    He, Yu-Cai
    Xu, Jian-He
    Pan, Jiang
    Ouyang, Li-Ming
    Xu, Yi
    [J]. BIOPROCESS AND BIOSYSTEMS ENGINEERING, 2008, 31 (05) : 445 - 451
  • [6] Cloning and biochemical properties of a highly thermostable and enantioselective nitrilase from Alcaligenes sp ECU0401 and its potential for (R)-(-)-mandelic acid production
    Zhang, Zhi-Jun
    Xu, Jian-He
    He, Yu-Cai
    Ouyang, Li-Ming
    Liu, You-Yan
    [J]. BIOPROCESS AND BIOSYSTEMS ENGINEERING, 2011, 34 (03) : 315 - 322
  • [7] Biocatalytic production of glycolic acid from glycolonitrile with a new bacterial isolate of Alcaligenes sp ECU0401
    He, Yu-Cai
    Xu, Jian-He
    [J]. JOURNAL OF BIOTECHNOLOGY, 2008, 136 : S369 - S370
  • [8] Bioproduction of Glycolic Acid from Glycolonitrile with a New Bacterial Isolate of Alcaligenes sp. ECU0401
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    Jian-He Xu
    Jin-Huan Su
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    [J]. Applied Biochemistry and Biotechnology, 2010, 160 : 1428 - 1440
  • [9] Bioproduction of Glycolic Acid from Glycolonitrile with a New Bacterial Isolate of Alcaligenes sp ECU0401
    He, Yu-Cai
    Xu, Jian-He
    Su, Jin-Huan
    Zhou, Li
    [J]. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2010, 160 (05) : 1428 - 1440
  • [10] Enantioselective biocatalytic hydrolysis of (R,S)-mandelonitrile for production of (R)-(-)-mandelic acid by a newly isolated mutant strain
    Xue, Ya-Ping
    Xu, Sai-Zhen
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    Zheng, Yu-Guo
    Shen, Yin-Chu
    [J]. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 2011, 38 (02) : 337 - 345
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