Moxifloxacin-induced multiple organ dysfunction possibly related to mutations in several genes involved in drug metabolism pathways

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作者
XIAO Yong-jiu [1 ,2 ]
SU Long-xiang [1 ,3 ]
ZHANG Xin [1 ]
XIE Li-xin [1 ,4 ]
机构
[1] Department of Respiratory Medicine,Hainan Branch of Chinese People's Liberation Army General Hospital
[2] Department of Respiratory Medicine,Lanzhou General Hospital of Lanzhou Military Area Command of Chinese People's Liberation Army
[3] Medical College of Nankai University
[4] Department of Respiratory Medicine,Chinese People's Liberation Army General Hospital
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中图分类号
R96 [药理学];
学科分类号
100602 ; 100706 ;
摘要
Quinolones have been used to treat various infectious diseases.The addition of fluorine atoms has allowed for extensive modifications of structures,which has enhanced the spectrum of activities and oral bioavailability of quinolones and resulted in the creation of fluoroquinolones.;Although the adverse effects associated with fluoroquinolone antibiotics have decreased considerably and these drugs are generally well
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页码:1396 / 1398
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  • [1] Moxifloxacin-induced multiple organ dysfunction possibly related to mutations in several genes involved in drug metabolism pathways
    Xiao Yong-jiu
    Su Long-xiang
    Zhang Xin
    Xie Li-xin
    [J]. CHINESE MEDICAL JOURNAL, 2013, 126 (07) : 1396 - 1398