A transgenic monkey model for the study of human brain evolution

被引：0
|
作者：
Lei Shi [1 ,2 ]
Bing Su [1 ,2 ,3 ]
机构：
[1] State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences
[2] Primate Research Center, Kunming Institute of Zoology, Chinese Academy of Sciences
[3] Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences
来源：
Zoological Research | 2019年 / 40卷 / 03期
基金：
中国国家自然科学基金;
关键词：
A transgenic monkey model for the study of human brain evolution;
D O I：
暂无
中图分类号：
Q987 [人类遗传学];
学科分类号：
071007 ;
摘要：
Why humans have large brains with higher cognitive abilities is a question long asked by scientists. However, much remains unknown, especially the underlying genetic mechanisms. With the use of a transgenic monkey model, we showed that human-specific sequence changes of a key brain development gene(Primary microcephaly 1, MCPH1) could result in detectable molecular and cognitive changes resembling human neoteny, a
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页码：236 / 238
页数：3
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