Neural stem cell transplantation in the repair of spinal cord injury

被引：0
|
作者：
Christopher IANNOTTI
吕晓斌
陆佩华
徐晓明
机构：
[1] China
[2] Department of Anatomy and Neurobiology
[3] Department of Neurobiology
[4] MO 63104
[5] Saint Louis University School of Medicine
[6] Shanghai 200025
[7] Shanghai Second Medical University
[8] St. Louis
[9] USA
[10] USA Department of Neurobiology
来源：
Progress in Natural Science:Materials International | 2001年 / 07期
基金：
美国国家卫生研究院;
关键词：
neural cell replacement; neural stem cells; spinal cord injury; transplantation;
D O I：
暂无
中图分类号：
R741 [神经病学];
学科分类号：
1002 ;
摘要：
Neural stem cells are a promising candidate for neural transplantation aimed at neural cell replacement and repair of the damaged host central nervous system (CNS). Recent studies using neural stem cells have shown that implanted neural stem cells can effectively incorporate into the damaged CNS and differentiate into neurons, astro-cytes, and oligodendrocytes. The recent explosion in the field of neural stem cell research has provided insight into the inductive factors influencing neural stem cell differentiation and may yield potential therapies for several neurological disorders, including spinal cord injury. In this review, we summarize recent studies involving neural stem cell biology in both rodents and humans. We also discuss unique advantages and possible mechanisms of using neural stem cell transplantation in the repair of spinal cord injury.
引用
收藏
页码：12 / 24+83-84
页数：15
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