Interaction of Copper in CuZn-Superoxide Dismutase With Histidine

被引：0
|
作者：
胡皆汉
舒占永
机构：
[1] PRC
[2] Dalian 116023
[3] Academia Sinica
[4] Dalian Institute of Chemical Physics
来源：
Science China Chemistry | 1994年 / Ser.B1994卷 / 03期
基金：
中国国家自然科学基金;
关键词：
CuZn-SOD; histidine; ESR; NMR;
D O I：
暂无
中图分类号：
O621 [有机化学一般性问题];
学科分类号：
070303 ; 081704 ;
摘要：
The interaction of CuZn-superoxide dismutase ( CuZn-SOD ) with the external histidine in aqueous solution has been studied in this work by ESR and NMR. It is found that the Cu(Ⅱ) of CuZn-SOD makes an exchanging interaction with the external substance in aqueous solution. Unlike in solid state, the Cu(Ⅱ) forms complex with external histidine, and keeps a motional equilibrium between the active centers and the complexes. Enzyme activity is also affected by this interaction. Some other amino acids are also discussed in this paper.
引用
收藏
页码：265 / 270 +385
页数：7
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