Semisynthesis of Strychnine N-oxide and Brucine N-oxide

被引：0

作者：

蔡宝昌

吴皓

王天山

宫代博继

服部征雄

机构：

[1] 日本国立富山医科药科大学和汉药研究所

[2] 南京中医药大学中医药研究院

来源：

Journal of Chinese Pharmaceutical Sciences | 1998年 / 03期

关键词：

马钱子炮制; 士的宁氮氧化物; 马钱子碱氮氧化物; 半合成;

D O I：

暂无

中图分类号：

R917 [药物分析];

学科分类号：

100704 ;

摘要：

用乙醇和过氧化氢，从士的宁和马钱子碱半合成了士的宁氮氧化物和马钱子碱氮氧化物。半合成的化合物根据１ＨＮＭＲ，１３ＣＮＭＲ，ＭＳ和１Ｈ１３ＣＮＭＲ得以确证。从士的宁半合成士的宁氮氧化物的得率为９３．５６％；从马钱子碱半合成马钱子碱氮氧化物的得率为９２．０２％。

引用

页码：57 / 58

页数：2

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