原发性高血压血清sICAM-1和sVCAM-1水平及意义

被引:0
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作者
沈华
蔡竞蕙
梁英妹
吴寒
机构
[1] 上海第一人民医院老年科
关键词
原发性高血压; 可溶性细胞间粘附分子-1; 可溶性血管间粘附分子-1;
D O I
暂无
中图分类号
R544.1 [高血压];
学科分类号
摘要
目的 检测老年早期原发性高血压患者血清可溶性细胞间粘附分子 1(sICAM 1)和可溶性血管间粘附分子 1(sVCAM 1)的水平并分析它们与老年原发性高血压的关系。  方法 用ELISA法测定老年原发性高血压患者、正常老年人、正常年轻人血清sICAM 1和sVCAM 1的浓度。  结果 老年原发性高血压血清sICAM 1和sV CAM 1的浓度高于正常老年人和正常年轻人 (P <0 0 1) ;另外正常老年人的sICAM 1和sVCAM 1的水平高于正常年轻人 (P <0 0 1)  结论 老年原发性高血压患者中血清sICAM 1,sVCAM 1的水平明显升高 ,提示在老年原发性高血压患者中存在内皮细胞结构和功能的改变。我们认为血清sICAM 1,sVCAM 1可作为原发性高血压病发展过程中内皮细胞功能紊乱的一个比较敏感的观察指标
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页码:127 / 129
页数:3
相关论文
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