Florbetapir 18F

被引:0
|
作者
赵文芳 [1 ]
董金华 [1 ]
机构
[1] 沈阳药科大学
关键词
淀粉样斑块; AD; 患者; Florbetapir; 阿尔兹海默病;
D O I
10.14142/j.cnki.cn21-1313/r.2012.05.003
中图分类号
R749.16 [];
学科分类号
100203 ;
摘要
Florbetapir18F(18F-AV-45)是由美国Eli Lilly and Company开发的一种放射性诊断剂,于2012年4月获美国FDA批准上市,其商品名为Amyvid。该药为注射剂,用于诊断阿尔茨海默病(Alzheimer’s disease,AD)或其他认知功能减退的疾病。
引用
收藏
页码:457 / 457
页数:1
相关论文
共 6 条
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  • [2] J Lister-James,MJ Pontecorvo,C Clark,AD Joshi,MA Mintun,W Zhang.Florbetapir F-18: a histopathologically validated beta-amyloid positron emission tomography imaging agent. Seminars in Nuclear Medicine . 2011
  • [3] AS Fleisher,K Chen,X Liu,A Roontiva,P Thiyyagura,N Ayutyanont.Using positron emission tomography and florbetapir F18 to image cortical amyloid in patients with mild cognitive impairment or dementia due to Alzheimer disease. Archives of Neurology . 2011
  • [4] ZHA Z,CHOI S R,PLOESSL K,et al.Multidentate 18 F-polypegylated styrylpyridines as imaging agents for Aβplaques in cerebral amyloid angiopathy (CAA). Journal of Medicinal Chemistry . 2011
  • [5] CM Clark,JA Schneider,BJ Bedell,TG Beach,WB Bilker,MA Mintun.Use of Florbetapir-PET for imaging β-amyloid pathology. JAMA: The Journal of the American Medical Association . 2011
  • [6] BENEDUM T,GOLDING G,LIM N,et al.Synthesis of 18 F-radiolabeled styrylpyridines from tosylate precursors and stable pharmaceutical compositions thereof. US,20100172836 . 2010